ISOC2 - isochorismatase domain containing 2 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 79763

About ISOC2

Cytogenetic location: 19q13.42 Genomic coordinates (GRCh38): 19:55,452,985-55,461,642 (from NCBI)

This gene has 8 transcripts (splice variants), 191 orthologues and 1 paralogue. Ubiquitous expression in kidney (RPKM 36.5), liver (RPKM 23.7) and 25 other tissues.

Summary

Involved in protein destabilization. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2022]

ISOC2 Products (3)

mRNA Protein Name
NM_001136201.2 NP_001129673.1 isochorismatase domain-containing protein 2 isoform 1
NM_001136202.2 NP_001129674.1 isochorismatase domain-containing protein 2 isoform 3
NM_024710.3 NP_078986.1 isochorismatase domain-containing protein 2 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
17658461 GOA
Biological Process GO Annotation Evidence References Source
involved in protein destabilization IMP
IMP: Inferred from mutant phenotype
17658461 GOA
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
17658461 GOA
located in nucleus IDA
IDA: Inferred from direct assay
17658461 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ISOC2 Protein Structure

Isochorismatase

Isochorismatase: Isochorismatase family (17 - 162)

  • 0
  • 100
  • 205 a.a.
Protein Preferred Names Protein Names

isochorismatase domain-containing protein 2

  • isochorismatase domain-containing protein 2, mitochondrial

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06938 ISOC2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus ISOC2 VGNC VGNC:30302
Rattus norvegicus ISOC2 RGD RGD:1592677
Canis familiaris ISOC2 VGNC VGNC:42113
Felis catus ISOC2 VGNC VGNC:62979
Others ISOC2 NCBI