CNTNAP3 - contactin associated protein family member 3 Gene

Also Known as CASPR3; CNTNAP3A

Species: Homo sapiens

Gene Type: protein coding

Gene ID: 79937

About CNTNAP3

Cytogenetic location: 9p12 Genomic coordinates (GRCh38): 9:39,064,710-39,288,167 (from NCBI)

This gene has 12 transcripts (splice variants), 289 orthologues and 35 paralogues. Broad expression in esophagus (RPKM 5.9), skin (RPKM 4.1) and 22 other tissues.

Summary

The protein encoded by this gene belongs to the NCP family of cell-recognition molecules. This family represents a distinct subgroup of the neurexins. NCP proteins mediate neuron-glial interactions in vertebrates and glial-glial contact in invertebrates. The protein encoded by this gene may play a role in cell recognition within the nervous system. Alternatively spliced transcript variants encoding different isoforms have been described but their biological nature has not been determined. [provided by RefSeq, Jul 2008]

CNTNAP3 Products (2)

mRNA	Protein	Name
NM_001393379.1	NP_001380308.1	contactin-associated protein-like 3 isoform 2 precursor
NM_033655.5	NP_387504.2	contactin-associated protein-like 3 isoform 1 precursor

CNTNAP3 Protein Structure

F5_F8_type_C

Laminin_G_2

0
200
400
600
800
1000
1200
1288 a.a.

Protein Preferred Names	Protein Names
contactin-associated protein-like 3	cell recognition molecule Caspr3

Related Diseases

Diseases	Alias
Cloacal Exstrophy	Oeis Complex Omphalocele-Cloacal Exstrophy-Imperforate Anus-Spinal Defect Syndrome Omphalocele, Exstrophy Of The Cloaca, Imperforate Anus, And Spinal Defects Compl Omphalocele, Exstrophy Of The Cloaca, Imperforate Anus, And Spinal Defects Complex Cloacal Exstrophy Sequence Omphalocele - Cloacal Exstrophy - Imperforate Anus - Spinal Defect Omphalocele, Exstrophy Of The Cloaca, Imperforate Anus, And Spinal Defects Omphalocele Exstrophy Imperforate Anus
Bladder Exstrophy-Epispadias-Cloacal Exstrophy Complex	Exstrophy-Epispadias Complex Bladder Exstrophy-Epispadias-Cloacal Extrophy Complex Beec Eec Exstrophy Of The Bladder Bladder Exstrophy Bladder Exstrophy And Epispadias Complex
Cyclothymic Disorder	Cyclothymia Cycloid Personality Cyclothymic Personality Affective Personality Disorder Cyclothymic Personality Disorder Cycloid Personality Disorder
Developmental And Epileptic Encephalopathy 76	DEE76 Epileptic Encephalopathy, Early Infantile, 76 Eiee76 Decam Developmental And Epileptic Encephalopathy, 76 Developmental Delay, Epileptic Encephalopathy, Cerebral Atrophy, And Abnormal Myelination Developmental Delay, Epileptic Endephalopathy, Cerebral Atrophy, And Abnormal Myelination Early Infantile Epileptic Encephalopathy 76
Bladder Exstrophy	Exstrophy Of The Bladder Classic Exstrophy Of The Bladder

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS02934	CNTNAP3 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown
HY-RS02935	CNTNAP3B Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	CNTNAP3	RGD	RGD:1563615
Mus musculus	CNTNAP3	MGD	MGI:3588199