NOL10 - nucleolar protein 10 Gene

Homo sapiens

Also known as PQBP5

Gene ID: 79954 | Gene type: protein coding

About NOL10

Cytogenetic location: 2p25.1 Genomic coordinates (GRCh38): 2:10,570,754-10,689,975 (from NCBI)

This gene has 22 transcripts (splice variants) and 202 orthologues. Ubiquitous expression in testis (RPKM 4.5), adrenal (RPKM 4.0) and 25 other tissues.

Summary

Enables RNA binding activity. Predicted to be involved in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Located in nucleolus. [provided by Alliance of Genome Resources, Apr 2022]

NOL10 Products(3)

mRNA	Protein	Name
NM_001261392.2	NP_001248321.1	nucleolar protein 10 isoform 2
NM_001261394.2	NP_001248323.1	nucleolar protein 10 isoform 3
NM_024894.4	NP_079170.2	nucleolar protein 10 isoform 1

NOL10 Protein Structure

NUC153

0
200
400
600
688 a.a.

Protein Preferred Names

Protein Names

nucleolar protein 10

H_NH0074G24.1

Related Diseases

Diseases

Alias

Renpenning Syndrome 1

Renpenning Syndrome	Golabi-Ito-Hall Syndrome
Mrxs3	Mrxs8
X-Linked Intellectual Disability Due To Pqbp1 Mutations	RENS1
Sutherland-Haan X-Linked Mental Retardation Syndrome	Shs
Mrx55	X-Linked Intellectual Disability, Renpenning Type
Sutherland-Haan Syndrome	Mental Retardation, X-Linked, Renpenning Type
Mental Retardation, X-Linked, With Spastic Diplegia	Mental Retardation, X-Linked, Syndromic 3
Mental Retardation, X-Linked, Syndromic 8	Mental Retardation, X-Linked 55
Syndromic X-Linked Mental Retardation 8	X-Linked Mental Retardation Renpenning Type
X-Linked Mental Retardation With Spastic Diplegia	Sutherland-Haan X-Linked Intellectual Disability Syndrome
X-Linked Intellectual Disability With Spastic Diplegia	Hamel Cerebropalatocardiac Syndrome
Porteous Syndrome	X-Linked Intellectual Deficit Due To Pqbp1 Mutations
X-Linked Intellectual Deficit, Renpenning Type	X-Linked Intellectual Disability, Sutherland-Haan Type
Hamel Cerebro-Palato-Cardiac Syndrome	Renpenning Syndrome, Type 1

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS09411	NOL10 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Rattus norvegicus	NOL10	RGD	RGD:1359447
Macaca mulatta	NOL10	VGNC	VGNC:75260
Canis familiaris	NOL10	VGNC	VGNC:43880
Mus musculus	NOL10	MGD	MGI:2684913
Bos taurus	NOL10	VGNC	VGNC:32154
Felis catus	NOL10	VGNC	VGNC:63850

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