PCDH11Y - protocadherin 11 Y-linked Gene

This gene belongs to the protocadherin family, a subfamily of the Cadherin superfamily. The encoded protein consists of an extracellular domain containing seven Cadherin repeats, a transmembrane domain, and a cytoplasmic tail that differs from those of the classical Cadherins. This gene is located on the Y chromosome in a block of X/Y homology and is very closely related to its paralog on the X chromosome. The protein is thought to play a role in cell-cell recognition during development of the central nervous system. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]