SYT15 - synaptotagmin 15 Gene

Also Known as sytXV; SYT15B; CHR10SYT

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 83849

About SYT15

Cytogenetic location: 10q11.22 Genomic coordinates (GRCh38): 10:46,579,128-46,597,108 (from NCBI)

This gene has 6 transcripts (splice variants), 178 orthologues and 31 paralogues. Broad expression in lung (RPKM 8.5), lymph node (RPKM 2.1) and 18 other tissues.

Summary

This gene encodes a member of the Synaptotagmin (Syt) family of membrane trafficking proteins. Members of this family contain a transmembrane region and a C-terminal-type tandem C2 domain. Unlike related family members, the encoded protein may be involved in membrane trafficking in non-neuronal tissues. Two trancript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

SYT15 Products (2)

mRNA Protein Name
NM_031912.5 NP_114118.2 synaptotagmin-15 isoform a
NM_181519.3 NP_852660.1 synaptotagmin-15 isoform b

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SYT15 Protein Structure

C2

C2: C2 domain (165 - 247)

C2

C2: C2 domain (295 - 382)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 421 a.a.
Protein Preferred Names Protein Names

synaptotagmin-15

  • chr10 synaptotagmin

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14112 SYT15 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus SYT15 MGD MGI:2442166
Rattus norvegicus SYT15 RGD RGD:727964