MYH16 - myosin heavy chain 16 pseudogene Gene

Also Known as MYH5; MHC20; MYH16P

Species: Homo sapiens

Gene Type: pseudo
Gene ID: 84176

About MYH16

Cytogenetic location: 7q22 Genomic coordinates (GRCh38): 7:98,400,001-107,800,000

This gene has 5 transcripts (splice variants). Low expression observed in reference dataset.

Summary

The MYH16 gene, encoding a sarcomeric Myosin heavy chain expressed in nonhuman primate masticatory muscles, is inactivated in humans. Stedman et al. (2004) [PubMed 15042088] hypothesized that the decrement in masticatory muscle size caused by the inactivation of MYH16 removed an evolutionary constraint on encephalization in early man.[supplied by OMIM, Mar 2008]