C15orf48 - chromosome 15 open reading frame 48 Gene

Also Known as MOCCI; NMES1; FOAP-11; MISTRAV; COXFA4L3; MIR147BHG

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 84419

About C15orf48

Cytogenetic location: 15q21.1 Genomic coordinates (GRCh38): 15:45,430,610-45,433,340 (from NCBI)

This gene has 4 transcripts (splice variants), 210 orthologues and 2 paralogues. Biased expression in colon (RPKM 233.7), small intestine (RPKM 89.5) and 9 other tissues.

Summary

This gene was first identified in a study of human esophageal squamous cell carcinoma tissues. Levels of both the message and protein are reduced in carcinoma samples. In adult human tissues, this gene is expressed in the the esophagus, stomach, small intestine, colon and placenta. Alternatively spliced transcript variants that encode the same protein have been identified. [provided by RefSeq, Jun 2012]

C15orf48 Products (2)

mRNA Protein Name
NM_032413.4 NP_115789.1 normal mucosa of esophagus-specific gene 1 protein
NM_197955.3 NP_922946.1 normal mucosa of esophagus-specific gene 1 protein

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32814053 GOA
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
12209954 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

C15orf48 Protein Structure

B12D

B12D: NADH-ubiquinone reductase complex 1 MLRQ subunit (9 - 76)

  • 0
  • 83 a.a.
Protein Preferred Names Protein Names

normal mucosa of esophagus-specific gene 1 protein

  • MIR147B host

Related Diseases

Diseases Alias
Squamous Cell Carcinoma

  • Epidermoid Carcinoma

  • Squamous Cell Cancer

  • Carcinoma, Squamous Cell

  • Squamous Cell Skin Cancer

  • Malignant Squamous Cell Tumor

  • Squamous Carcinoma

  • Squamous Cell Epithelioma

  • Carcinoma Squamous Cell

  • Neoplasms, Squamous Cell

  • Squamous Cell Carcinoma - Category

  • Malignant Squamous Cell Neoplasm

  • Squamous Cell Carcinoma Of Skin
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01700 C15orf48 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Canis familiaris C15orf48 VGNC VGNC:59105
Rattus norvegicus C15orf48 RGD RGD:1359583
Bos taurus C15orf48 VGNC VGNC:52612
Mus musculus C15orf48 MGD MGI:3034182
Felis catus C15orf48 VGNC VGNC:81016
Others C15orf48 NCBI