GJA10 - gap junction protein alpha 10 Gene

Also Known as CX62

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 84694

About GJA10

Cytogenetic location: 6q15 Genomic coordinates (GRCh38): 6:89,894,469-89,896,120 (from NCBI)

This gene has 3 transcripts (splice variants), 1 gene allele, 254 orthologues and 20 paralogues.

Summary

Connexins, such as GJA10, are involved in the formation of gap junctions, intercellular conduits that directly connect the cytoplasms of contacting cells. Each gap junction channel is formed by docking of 2 hemichannels, each of which contains 6 connexin subunits (Sohl et al., 2003 [PubMed 12881038]).[supplied by OMIM, Mar 2008]

GJA10 Products (1)

mRNA Protein Name
NM_032602.2 NP_115991.1 gap junction alpha-10 protein

GJA10 Protein Structure

Connexin

Connexin: Connexin (3 - 108)

(167 - 233)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 543 a.a.
Protein Preferred Names Protein Names

gap junction alpha-10 protein

  • connexin 62

Related Diseases

Diseases Alias
Deafness, Autosomal Dominant 66

  • DFNA66

  • Autosomal Dominant Nonsyndromic Deafness 66

  • Autosomal Dominant Deafness 66

  • Deafness, Autosomal Dominant, 66
Noonan Syndrome 5

  • NS5

  • Noonan Syndrome, Type 5
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05441 GJA10 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus GJA10 MGD MGI:1339969
Felis catus GJA10 VGNC VGNC:62562
Canis familiaris GJA10 VGNC VGNC:41232
Macaca mulatta GJA10 VGNC VGNC:72952
Rattus norvegicus GJA10 RGD RGD:1309630
Bos taurus GJA10 VGNC VGNC:29371
Others GJA10 NCBI