NOP14 - NOP14 nucleolar protein Gene

Also Known as UTP2; NOL14; C4orf9; RES425; RES4-25

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 8602

About NOP14

Cytogenetic location: 4p16.3 Genomic coordinates (GRCh38): 4:2,937,936-2,963,406 (from NCBI)

This gene has 5 transcripts (splice variants) and 199 orthologues. Ubiquitous expression in lymph node (RPKM 10.9), appendix (RPKM 9.8) and 25 other tissues.

Summary

This gene encodes a protein that plays a role in pre-18s rRNA processing and small ribosomal subunit assembly. The encoded protein may be involved in the regulation of pancreatic Cancer cell proliferation and migration. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]

NOP14 Products (3)

mRNA Protein Name
NM_001291978.2 NP_001278907.1 nucleolar protein 14 isoform 1
NM_001291979.2 NP_001278908.1 nucleolar protein 14 isoform 2
NM_003703.3 NP_003694.1 nucleolar protein 14 isoform 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables enzyme binding IPI
IPI: Inferred from physical interaction
23382074 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

NOP14 Protein Structure

Nop14

Nop14: Nop14-like family (26 - 847)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 857 a.a.
Protein Preferred Names Protein Names

nucleolar protein 14

  • NOP14 nucleolar protein homolog

Related Diseases

Diseases Alias
Bowen-Conradi Syndrome

  • BWCNS

  • Bowen Hutterite Syndrome

  • Bowen-Conradi Hutterite Syndrome

  • Bowen Syndrome, Hutterite Type

  • Bowen Hutterite Syndrome, Formerly

  • Hutterite Syndrome

  • Bowen Syndrome Hutterite Type

  • Fetal Growth Retardation
Pancreatic Cancer

  • Pancreatic Carcinoma

  • Carcinoma Of Pancreas

  • Familial Pancreatic Carcinoma

  • Pancreatic Neoplasm

  • Pancreatic Carcinoma, Familial

  • Malignant Neoplasm Of Pancreas

  • Pancreatic Acinar Carcinoma

  • Pancreatic Tumor

  • Familial Pancreatic Cancer

  • Neoplasm Of The Pancreas

  • Cancer Of The Pancreas

  • Pancreatic Carcinoma, Somatic

  • Pancreatic Cancer, Somatic

  • Ca Body Of Pancreas

  • Ca Head Of Pancreas

  • Ca Tail Of Pancreas

  • Malignant Neoplasm Of Body Of Pancreas

  • Malignant Neoplasm Of Head Of Pancreas

  • Malignant Neoplasm Of Tail Of Pancreas

  • Pancreas Neoplasm

  • Exocrine Cancer

  • Exocrine Pancreas Carcinoma

  • Hereditary Pancreatic Cancer

  • Hereditary Pancreatic Carcinoma

  • PNCA

  • Pancreatic Cancer, Susceptibility To

  • Carcinoma Of Head Of Pancreas

  • Pancreatic Neoplasms

  • Pancreatic Tumors

  • Cancer, Pancreatic

  • Cancer Of Pancreas

  • Mixed Islet Cell With Exocrine Carcinoma Of Unspecified Site
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09427 NOP14 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22681 Nop14 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29195 Nop14 Rat Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta NOP14 VGNC VGNC:75194
Bos taurus NOP14 VGNC VGNC:32165
Rattus norvegicus NOP14 RGD RGD:1305605
Canis familiaris NOP14 VGNC VGNC:43887
Mus musculus NOP14 MGD MGI:1922666
Felis catus NOP14 VGNC VGNC:63856
Others NOP14 NCBI