2. Gene
  3. TESMIN - testis expressed metallothionein like protein Gene

TESMIN - testis expressed metallothionein like protein Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens

Also known as MTL5; MTLT; CXCDC2

Gene ID: 9633 | Gene type: protein coding

About TESMIN

Cytogenetic location: 11q13.3 Genomic coordinates (GRCh38): 11:68,704,796-68,751,520 (from NCBI)

This gene has 9 transcripts (splice variants), 129 orthologues and 1 paralogue. Biased expression in testis (RPKM 13.9), bone marrow (RPKM 1.4) and 2 other tissues.

Summary

Metallothionein proteins are highly conserved low-molecular-weight cysteine-rich proteins that are induced by and bind to heavy metal ions and have no enzymatic activity. They may play a central role in the regulation of cell growth and differentiation and are involved in spermatogenesis. This gene encodes a metallothionein-like protein which has been shown to be expressed differentially in mouse testis and ovary. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

TESMIN Products(2)

mRNA Protein Name
NM_001039656.1 NP_001034745.1 tesmin isoform b
NM_004923.3 NP_004914.2 tesmin isoform a

TESMIN Protein Structure

TCR

TCR: Tesmin/TSO1-like CXC domain, cysteine-rich domain (306 - 330)

TCR

TCR: Tesmin/TSO1-like CXC domain, cysteine-rich domain (365 - 405)

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  • 508 a.a.
Protein Preferred Names Protein Names

tesmin

CXC domain containing 2

Related Diseases

Diseases Alias
Childhood B-Cell Acute Lymphoblastic Leukemia

B-Cell Childhood Acute Lymphoblastic Leukemia
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS14382 TESMIN Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus TESMIN VGNC VGNC:68342
Macaca mulatta TESMIN VGNC VGNC:79965
Rattus norvegicus TESMIN RGD RGD:1309788
Mus musculus TESMIN MGD MGI:1340029
Canis familiaris TESMIN VGNC VGNC:47258
Bos taurus TESMIN VGNC VGNC:106972