TESMIN - testis expressed metallothionein like protein Gene

Also Known as MTL5; MTLT; CXCDC2

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 9633

About TESMIN

Cytogenetic location: 11q13.3 Genomic coordinates (GRCh38): 11:68,704,796-68,751,520 (from NCBI)

This gene has 9 transcripts (splice variants), 129 orthologues and 1 paralogue. Biased expression in testis (RPKM 13.9), bone marrow (RPKM 1.4) and 2 other tissues.

Summary

Metallothionein proteins are highly conserved low-molecular-weight cysteine-rich proteins that are induced by and bind to heavy metal ions and have no enzymatic activity. They may play a central role in the regulation of cell growth and differentiation and are involved in spermatogenesis. This gene encodes a metallothionein-like protein which has been shown to be expressed differentially in mouse testis and ovary. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

TESMIN Products (2)

mRNA Protein Name
NM_001039656.1 NP_001034745.1 tesmin isoform b
NM_004923.3 NP_004914.2 tesmin isoform a

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

TESMIN Protein Structure

TCR

TCR: Tesmin/TSO1-like CXC domain, cysteine-rich domain (306 - 330)

TCR

TCR: Tesmin/TSO1-like CXC domain, cysteine-rich domain (365 - 405)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 508 a.a.
Protein Preferred Names Protein Names

tesmin

  • CXC domain containing 2

Related Diseases

Diseases Alias
Childhood B-Cell Acute Lymphoblastic Leukemia

  • B-Cell Childhood Acute Lymphoblastic Leukemia
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS14382 TESMIN Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus TESMIN VGNC VGNC:68342
Macaca mulatta TESMIN VGNC VGNC:79965
Rattus norvegicus TESMIN RGD RGD:1309788
Mus musculus TESMIN MGD MGI:1340029
Canis familiaris TESMIN VGNC VGNC:47258
Bos taurus TESMIN VGNC VGNC:106972
Others TESMIN NCBI