NRK - Nik related kinase Gene

Also Known as NESK

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 203447

About NRK

Cytogenetic location: Xq22.3 Genomic coordinates (GRCh38): X:105,821,786-105,958,610 (from NCBI)

This gene has 4 transcripts (splice variants), 96 orthologues and 35 paralogues. Biased expression in ovary (RPKM 15.5), placenta (RPKM 15.0) and 8 other tissues.

Summary

The mouse ortholog of this gene encodes a protein kinase required for JNK activation. The encoded protein may be involved in the induction of actin polymerization in late embryogenesis.[provided by RefSeq, Jun 2010]

NRK Products (1)

mRNA Protein Name
NM_198465.4 NP_940867.2 nik-related protein kinase

NRK Protein Structure

Pkinase

Pkinase: Protein kinase domain (26 - 313)

CNH

CNH: CNH domain (1213 - 1548)

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  • 1582 a.a.
Protein Preferred Names Protein Names

nik-related protein kinase

Related Diseases

Diseases Alias
Hypermobility Syndrome

  • Benign Joint Hypermobility
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (14)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-147716 CDK8-IN-6 Inhibitor / Unkown
HY-147717 CDK8-IN-7 Inhibitor / Unkown
HY-168860 Antituberculosis agent-13 Inhibitor / Unkown
HY-170540 NOX4-IN-1 Inhibitor / Unkown
HY-176019 Methylcarbamyl PAF C-8 / Unkown
HY-179378 XRF-1021 Inhibitor / Unkown
HY-N17923 Crocusatin R / Unkown
HY-RS09574 NRK Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-125322 Reveromycin C / Unkown
HY-N14658 Phosmidosine B / Unkown
HY-N15110 Phosmidosine Inhibitor / Unkown
HY-N5190 Enamidonin Inhibitor / Unkown
HY-RS16266 Nrk Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26064 Nrk Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus NRK VGNC VGNC:97537
Rattus norvegicus NRK RGD RGD:1566163
Canis familiaris NRK VGNC VGNC:43971
Mus musculus NRK MGD MGI:1351326
Macaca mulatta NRK VGNC VGNC:81488
Others NRK NCBI