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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
13 Results for "
GHS-R1a
" in MedChemExpress (MCE) Product Catalog:
Products (13)
13 Results for "GHS-R1a" in MCE Product Catalog:
3
3 Cited Publications
Cat. No.: HY-U00433
CAS No.: 925238-89-7
Target:
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JMV 2959 is a growth hormone secretagogue receptor type 1a (GHS-R1a) antagonist with an IC50 of 32 nM.
3
3 Cited Publications
Cat. No.: HY-U00433A
CAS No.: 2448414-54-6
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JMV 2959 hydrochloride is a growth hormone secretagogue receptor type 1a (GHS-R1a) antagonist with an IC50 of 32±3 nM in LLC-PK1 cells.
1
1 Cited Publications
Cat. No.: HY-P5645
CAS No.: 1683582-94-6
Synonyms: Human liver expressed antimicrobial peptide-2
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Cat. No.: HY-50760
CAS No.: 145455-35-2
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L-692585 is a potent and nonpeptidyl growth hormone secretagogue receptor (GHS-R1a) agonist, with a Ki of 0.8 nM. L-692585 acts directly on somatotropes causing GH release [1] .
Cat. No.: HY-P1139
CAS No.: 485803-62-1
Synonyms: PCFWKTCK
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Cat. No.: HY-153095
CAS No.: 2857112-06-0
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PF-6870961 is an inverse agonist of GHSR1a with Ki values of 73.6 nM (human GHSR), 239 nM (rat GHSR), and 217 nM (dog GHSR), respectively. PF-6870961 inhibits the constitutive GHSR1a-induced IP accumulation with an IC50 value of 300 nM. PF-6870961 also inhibits constitutive GHSR1a β-arrestin mobilization with an IC50 value of 1.10 nM [1].
Cat. No.: HY-137061
CAS No.: 1143020-91-0
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AZ-GHS-22 is a potent, non-CNS penetrant GHS-R1a inverse agonist (IC50=0.77 nM) [1].
Cat. No.: HY-173271
CAS No.: 3060887-25-1
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GHSR-1a agonist-1 (Compound 4b) is an orally active agonist of the human growth hormone secretagogue receptor 1a (GHSR-1a), with an EC50 of 0.49 nM. GHSR-1a agonist-1 can effectively stimulate the release of endogenous growth hormone by activating GHSR-1a. GHSR-1a agonist-1 administered orally at a dose as low as 0.1 mg/kg can increase the body weight and body length of 4-week-old rats. GHSR-1a agonist-1 can be used in the research field of growth and development retardation in children [1].
Cat. No.: HY-129287
CAS No.: 925239-09-4
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JMV 3008 is a GHS-R1a antagonist with an IC50 of 5.6 nM. JMV 3008 can be used in the research of diseases such as diabetes and obesity [1].
Cat. No.: HY-RS05416
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GHSR Human Pre-designed siRNA Set A contains three designed siRNAs for GHSR gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-153095A
CAS No.: 2857112-07-1
Target:
Research Areas:
PF-6870961 hydrochloride is an inverse agonist of GHSR1a with Ki values of 73.6 nM (human GHSR), 239 nM (rat GHSR), and 217 nM (dog GHSR), respectively. PF-6870961 hydrochloride inhibits the constitutive GHSR1a-induced IP accumulation with an IC50 value of 300 nM. PF-6870961 hydrochloride also inhibits constitutive GHSR1a β-arrestin mobilization with an IC50 value of 1.10 nM [1].
Cat. No.: HY-RS05417
Target:
Research Areas:
Ghsr Mouse Pre-designed siRNA Set A contains three designed siRNAs for Ghsr gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-176995
CAS No.: 1143021-16-2
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AZ-GHS-38 (compound 38) is an orally active CNS-penetrant inverse agonist of growth hormone secretagogue receptor (GHS-R1a) with an IC50 of 6.7 nM. AZ-GHS-38 results in acute reduction of food intake in wild-type mice. AZ-GHS-38 can be used for anti-obesity research [1].
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
