145455-35-2
145455-35-2
Chemical Structure
L-692585
- CAS No.: 145455-35-2
- Formula:C32H37N7O3
- Molecular Weight:567.68
IUPAC Name: N-((R)-1-((2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-3-yl)-3-(((R)-2-hydroxypropyl)amino)-3-methylbutanamide
InChIKey: AYBCFPXLXOLPIZ-JIPXPUAJSA-N
SMILES: CC(C)(NC[C@H](O)C)CC(N[C@H]1C(N(CC2=CC=C(C3=CC=CC=C3C4=NN=NN4)C=C2)C5=CC=CC=C5CC1)=O)=O
Biological Activity: L-692585 is a potent and nonpeptidyl growth hormone secretagogue receptor (GHS-R1a) agonist, with a Ki of 0.8 nM. L-692585 acts directly on somatotropes causing GH release[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
L-692585 | 98.94% | L-692585 is a potent and nonpeptidyl growth hormone secretagogue receptor (GHS-R1a) agonist, with a Ki of 0.8 nM. L-692585 acts directly on somatotropes causing GH release. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. Smith RG, et, al. Peptidomimetic regulation of growth hormone secretion. Endocr Rev. 1997 Oct; 18(5): 621-45. [Content Brief]
- [2]. Glavaski-Joksimovic A, et, al. Mechanism of action of the growth hormone secretagogue, L-692,585, on isolated porcine somatotropes. J Endocrinol. 2002 Dec; 175(3): 625-36. [Content Brief]
Keywords
