3060887-25-1
Chemical Structure
GHSR-1a agonist-1
- CAS No.: 3060887-25-1
- Formula:C30H37N5O4
- Molecular Weight:531.65
InChIKey: VPCWMOIIHNWVCH-AYWVHJORSA-N
SMILES: O=C(N(CCC1=NN(C2=O)C3CC3)C[C@]12CC4=CC=CC=C4)[C@@H](COCC5=CC=CC=C5)NC(C(N)(C)C)=O
Biological Activity: GHSR-1a agonist-1 (Compound 4b) is an orally active agonist of the human growth hormone secretagogue receptor 1a (GHSR-1a), with an EC50 of 0.49 nM. GHSR-1a agonist-1 can effectively stimulate the release of endogenous growth hormone by activating GHSR-1a. GHSR-1a agonist-1 administered orally at a dose as low as 0.1 mg/kg can increase the body weight and body length of 4-week-old rats. GHSR-1a agonist-1 can be used in the research field of growth and development retardation in children[1].
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GHSR-1a agonist-1 | GHSR-1a agonist-1 (Compound 4b) is an orally active agonist of the human growth hormone secretagogue receptor 1a (GHSR-1a), with an EC50 of 0.49 nM. GHSR-1a agonist-1 can effectively stimulate the release of endogenous growth hormone by activating GHSR-1a. GHSR-1a agonist-1 administered orally at a dose as low as 0.1 mg/kg can increase the body weight and body length of 4-week-old rats. GHSR-1a agonist-1 can be used in the research field of growth and development retardation in children. | |||||||||||||||||||||
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Keywords
