1143021-16-2
1143021-16-2
Chemical Structure
AZ-GHS-38
- CAS No.: 1143021-16-2
- Formula:C25H28ClN5O5S2
- Molecular Weight:578.10
InChIKey: XEOOLDLJXYEALJ-UHFFFAOYSA-N
SMILES: O=C(NC1=NC2=C(S1)C=C(S(=O)(C3CCN(CC3)C)=O)C=C2)NC(C4=CC(N5CCOCC5)=CC=C4Cl)=O
Biological Activity: AZ-GHS-38 (compound 38) is an orally active CNS-penetrant inverse agonist of growth hormone secretagogue receptor (GHS-R1a) with an IC50 of 6.7 nM. AZ-GHS-38 results in acute reduction of food intake in wild-type mice. AZ-GHS-38 can be used for anti-obesity research[1].
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AZ-GHS-38 | AZ-GHS-38 (compound 38) is an orally active CNS-penetrant inverse agonist of growth hormone secretagogue receptor (GHS-R1a) with an IC50 of 6.7 nM. AZ-GHS-38 results in acute reduction of food intake in wild-type mice. AZ-GHS-38 can be used for anti-obesity research. | |||||||||||||||||||||
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References
Keywords
