水酸化アルミニウム
Based on 7 publication(s) in Google Scholar
Aluminum Hydroxide is an orally active main form of aluminum used as adjuvant. Aluminum hydroxide-based adjuvant researches include the repository effect, pro-phagocytic effect, and activation of the pro-inflammatory NLRP3 pathway. Aluminum Hydroxide also acts as adjuvant to compensate low inherent immunogenicity of subunit vaccines.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 97.0%
- CAS 番号: 21645-51-2
- 分子式: Al(OH)3
- 分子量:78.00
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保管条件:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
MedChemExpress（MCE）の使用を引用している文献 Aluminum Hydroxide
More- J Control Release. 2026 May 10:393:114809. [Abstract]
- Phytomedicine. 2025 Apr:139:156508. [Abstract]
- J Transl Int Med. 2021 Aug 24;11(3):282-293. [Abstract]
- Biochem Pharmacol. 2026 Apr:246:117701. [Abstract]
- Arch Biochem Biophys. 2025 Jun 9:110502. [Abstract]
- Immunobiology. 2025 Jul 16;230(4):153103. [Abstract]
- Biosci Biotechnol Biochem. 2020 Jul;84(7):1409-1417. [Abstract]
生物活性
Aluminum Hydroxide is not recommended to be freezed when used as the vaccine adjuvant to avoid reducing the immunogenicity of the vaccine.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
化学情報
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CAS 番号 21645-51-2
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性状 Solid
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分子量 78.00
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分子式 Al(OH)3
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Color White to off-white
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SMILES
O[Al](O)O
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別名
Aluminum Hydroxide
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Publications (7)
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Journal Impact Factor
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Most Recent
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J Control Release
Dual-action nasal spray with mussel protein and xylitol restores epithelial barrier and attenuates type 2 inflammation in allergic rhinitis. [Abstract]2026 May 10:393:114809. PMID: 41819426 -
Phytomedicine
Jieyu Guben decoction alleviates combined allergic rhinitis and asthma syndrome by balancing Th17/Treg expression and restoring PPARD. [Abstract]2025 Apr:139:156508. PMID: 40031093 -
J Transl Int Med
MiR-182/Sestrin2 affects the function of asthmatic airway smooth muscle cells by the AMPK/mTOR pathway. [Abstract]2021 Aug 24;11(3):282-293. PMID: 37662894 -
Biochem Pharmacol
TTC3-mediated ubiquitination of APPL1 is suppression involved in the anti-asthmatic effects of the substance P receptor antagonist WIN62577. [Abstract]2026 Apr:246:117701. PMID: 41520735 -
Arch Biochem Biophys
Targeting IL-33 to suppress ferroptosis and alleviate inflammation in asthma exacerbations. [Abstract]2025 Jun 9:110502. PMID: 40499633 -
Immunobiology
Exosomes derived from baicalin-pretreated bone marrow mesenchymal stem cells inactivate the TLR4/MyD88/NF-kB pathway to improve asthma. [Abstract]2025 Jul 16;230(4):153103. PMID: 40695068 -
Biosci Biotechnol Biochem
Bulleyaconitine A inhibits the lung inflammation and airway remodeling through restoring Th1/Th2 balance in asthmatic model mice. [Abstract]2020 Jul;84(7):1409-1417. PMID: 32290781
溶剤 & 溶解度
H2O : < 0.1 mg/mL (insoluble)
DMSO : < 1 mg/mL (insoluble or slightly soluble)
For the following dissolution methods, please prepare the working solution directly:
It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 0.5% CMC-Na/saline water
Solubility: 10 mg/mL (128.21 mM); Suspended solution; Need ultrasonic
純度とドキュメンテーション
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データシート (274 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. He P, et al. Advances in aluminum hydroxide-based adjuvant research and its mechanism. Hum Vaccin Immunother. 2015;11(2):477-88. [Content Brief]
[2]. Amini Y, et al. Aluminum hydroxide nanoparticles show strong activity to stimulate Th-1 immune response against tuberculosis. Artif Cells Nanomed Biotechnol. 2017 Nov;45(7):1331-1335. [Content Brief]
[3]. Ohtawa M, et al. Effect of aluminum ingestion on lipid peroxidation in rats. Chem Pharm Bull (Tokyo). 1983 Apr;31(4):1415-8. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Aluminum Hydroxide 関連分類
HY-B1521 関連分類
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