21645-51-2
21645-51-2
Chemical Structure
Aluminum Hydroxide
- CAS No.: 21645-51-2
- Formula:Al(OH)3
- Molecular Weight:78.00
IUPAC Name: trihydroxyaluminum
InChIKey: WNROFYMDJYEPJX-UHFFFAOYSA-K
SMILES: O[Al](O)O
Biological Activity: Aluminum Hydroxide is an orally active main form of aluminum used as adjuvant. Aluminum hydroxide-based adjuvant researches include the repository effect, pro-phagocytic effect, and activation of the pro-inflammatory NLRP3 pathway. Aluminum Hydroxide also acts as adjuvant to compensate low inherent immunogenicity of subunit vaccines[1][2].
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Aluminum Hydroxide | 97.0% | Aluminum Hydroxide is an orally active main form of aluminum used as adjuvant. Aluminum hydroxide-based adjuvant researches include the repository effect, pro-phagocytic effect, and activation of the pro-inflammatory NLRP3 pathway. Aluminum Hydroxide also acts as adjuvant to compensate low inherent immunogenicity of subunit vaccines. | ||||||||||||||||||||
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Dried aluminum hydroxide gel,United States Pharmacopeia (USP) Reference Standard | Dried aluminum hydroxide gel, United States Pharmacopeia (USP) Reference Standard is a commonly used antacid with remarkable compound adhesion and release activity. Dried aluminum hydroxide gel, United States Pharmacopeia (USP) Reference Standard can effectively neutralize gastric acid and relieve stomach discomfort. Dried aluminum hydroxide gel, United States Pharmacopeia (USP) Reference Standard is also often used as an adjuvant in vaccines to enhance immune responses. Dried aluminum hydroxide gel, United States Pharmacopeia (USP) Reference Standard can improve the stability and bioavailability of compounds in preparations. | |||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.70
HY-Y0498Aluminum oxide -
Similarity Score 0.62
HY-153217Arsonic acid -
Similarity Score 0.62
HY-B2217Calcium hydroxide -
Similarity Score 0.62
HY-B2218DMagnesium hydroxide, 99%(KT) -
Similarity Score 0.62
HY-W105988Copper dihydroxide -
Similarity Score 0.62
HY-W019872Ammonium dihydrogen phosphate -
Similarity Score 0.62
HY-W134021Manganese dihydrogen phosphate -
Explore the MedChemAI to find more analogs
References
- [1]. He P, et al. Advances in aluminum hydroxide-based adjuvant research and its mechanism. Hum Vaccin Immunother. 2015;11(2):477-88. [Content Brief]
- [2]. Amini Y, et al. Aluminum hydroxide nanoparticles show strong activity to stimulate Th-1 immune response against tuberculosis. Artif Cells Nanomed Biotechnol. 2017 Nov;45(7):1331-1335. [Content Brief]
