Cytosine-d2
Based on 1 Customer Validation
Cytosine-d2 is the deuterium labeled Cytosine. Cytosine is one of the four main bases found in DNA and RNA. Cytosine modifications exhibit circadian oscillations that are involved in epigenetic diversity and aging.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.69%
- CAS 番号: 106391-24-6
- 分子式: C4H3D2N3O
- 分子量:113.11
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保管条件:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
Endogenous Metabolite アイソフォーム固有の製品をすべて表示
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生物活性
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
化学情報
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CAS 番号 106391-24-6
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非標識Cas 71-30-7
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性状 Solid
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分子量 113.11
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分子式 C4H3D2N3O
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Color White to off-white
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SMILES
NC(N1)=C([2H])C([2H])=NC1=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
溶剤 & 溶解度
DMSO : 10 mg/mL (88.41 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (273 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. Maxam AM, et, al. A new method for sequencing DNA. Proc Natl Acad Sci U S A. 1977 Feb;74(2):560-4. [Content Brief]
[3]. Oh G, et, al. Cytosine modifications exhibit circadian oscillations that are involved in epigenetic diversity and aging. Nat Commun. 2018 Feb 13;9(1):644. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 8.8410 mL | 44.2048 mL | 88.4095 mL | 221.0238 mL |
| 5 mM | 1.7682 mL | 8.8410 mL | 17.6819 mL | 44.2048 mL | |
| 10 mM | 0.8841 mL | 4.4205 mL | 8.8410 mL | 22.1024 mL | |
| 15 mM | 0.5894 mL | 2.9470 mL | 5.8940 mL | 14.7349 mL | |
| 20 mM | 0.4420 mL | 2.2102 mL | 4.4205 mL | 11.0512 mL | |
| 25 mM | 0.3536 mL | 1.7682 mL | 3.5364 mL | 8.8410 mL | |
| 30 mM | 0.2947 mL | 1.4735 mL | 2.9470 mL | 7.3675 mL | |
| 40 mM | 0.2210 mL | 1.1051 mL | 2.2102 mL | 5.5256 mL | |
| 50 mM | 0.1768 mL | 0.8841 mL | 1.7682 mL | 4.4205 mL | |
| 60 mM | 0.1473 mL | 0.7367 mL | 1.4735 mL | 3.6837 mL | |
| 80 mM | 0.1105 mL | 0.5526 mL | 1.1051 mL | 2.7628 mL |
Cytosine-d2 関連分類
HY-I0626S2 関連分類
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