71-30-7
71-30-7
Chemical Structure
Cytosine
- CAS No.: 71-30-7
- Formula:C4H5N3O
- Molecular Weight:111.10
IUPAC Name: 4-aminopyrimidin-2(1H)-one
InChIKey: OPTASPLRGRRNAP-UHFFFAOYSA-N
SMILES: O=C1NC=CC(N)=N1
Biological Activity: Cytosine is one of the four main bases found in DNA and RNA. Cytosine modifications exhibit circadian oscillations that are involved in epigenetic diversity and aging. Cytosine can be used in cancer research[1][2][3][4].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Cytosine | 99.97% | Cytosine is one of the four main bases found in DNA and RNA. Cytosine modifications exhibit circadian oscillations that are involved in epigenetic diversity and aging. Cytosine can be used in cancer research. | ||||||||||||||||||||
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Cytosine (Standard) | 99.94% | Cytosine (Standard) is the analytical standard of Cytosine. This product is intended for research and analytical applications. Cytosine is one of the four main bases found in DNA and RNA. Cytosine modifications exhibit circadian oscillations that are involved in epigenetic diversity and aging. | ||||||||||||||||||||
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Cytosine-d2 | 99.97% | Cytosine-d2 is the deuterium labeled Cytosine. Cytosine is one of the four main bases found in DNA and RNA. Cytosine modifications exhibit circadian oscillations that are involved in epigenetic diversity and aging. | ||||||||||||||||||||
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Cytosine-13C2,15N3 | Cytosine-13C2,15N3 is the 13C-labeled and 15N-labeled Cytosine. Cytosine is one of the four main bases found in DNA and RNA. Cytosine modifications exhibit circadian oscillations that are involved in epigenetic diversity and aging. | |||||||||||||||||||||
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Cytosine-13C,15N2 | 98% | Cytosine-13C,15N2 is the 13C and 15N labeled Cytosine. Cytosine is one of the four main bases found in DNA and RNA. Cytosine modifications exhibit circadian oscillations that are involved in epigenetic diversity and aging. | ||||||||||||||||||||
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Amifampridine-d3 | Amifampridine-d3 (3,4-Diaminopyridine-d3) is deuterium labeled Amifampridine. Amifampridine (3,4-Diaminopyridine) is an orally active, potent and cell permeable voltage-gated potassium (Kv) channel blocker (PCB). Amifampridine is efficacy in the reversal of BoNT/A (HY-P79153) intoxication. Amifampridine increases transmitter release from neuromuscular junctions (NMJs). Amifampridine can be used for Lambert-Eaton myasthenic syndrome (LEMS) research. | |||||||||||||||||||||
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Uracil 4,5-13C2 | Uracil 4,5-13C2 is the 13C labeled Uracil. | |||||||||||||||||||||
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4-Amino-2-chloropyrimidine | 99.77% | 4-Amino-2-chloropyrimidine is a pyrimidine derivative. 4-Amino-2-chloropyrimidine is a competitive inhibitor for AChE (Ki = 0.18 μM) and BChE (Ki = 1.324 μM). 4-Amino-2-chloropyrimidine fits in the binding pocket of 4BDS. 4-Amino-2-chloropyrimidine has high inhibitory activity on GST enzyme activity (IC50 = 0.037 μM, Ki = 0.047 μM) in vitro. | ||||||||||||||||||||
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4-Amino-3-methylpyridine-d3 | 4-Amino-3-methylpyridine-d3 is the deuterium labeled 4-Amino-3-methylpyridine. | |||||||||||||||||||||
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5-Aminopyrimidine-d3 | 5-Aminopyrimidine-d3 is the deuterated form of 5-Aminopyrimidine. 5-Aminopyrimidine is a biochemical reagent that can serve as a biomaterial or an organic compound for research related to life sciences. Its derivatives exhibit antioxidant activity. | |||||||||||||||||||||
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Flucytosine | 99.97% | Flucytosine (5-Fluorocytosine) is an antifungal compound with oral activity. Flucytosine is a widely used cytotoxic drug that, after further metabolism, produces fluorinated ribonucleotides and deoxyribonucleotides, inhibits DNA and protein synthesis, and has multiple effects such as inhibiting candida and candida neoplasm infection and producies cytotoxicity to cancer cells. | ||||||||||||||||||||
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Flucytosine-13C,15N2 | Flucytosine-13C,15N2 (NSC 103805-13C,15N2; Ro 2-9915-13C,15N2) is a 13C- and 15N-labeled Flucytosine (HY-B0139). | |||||||||||||||||||||
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Uracil-13C2,15N2 | Uracil-13C2,15N2 is the 13C-labeled and 15N-labeled Uracil. Uracil is a common and naturally occurring pyrimidine derivative and one of the four nucleobases in the nucleic acid of RNA. | |||||||||||||||||||||
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Uracil-13C4,15N2 | 98.0% | Uracil-13C4,15N2 is the 13C and 15N labeled Uracil. Uracil is a common and naturally occurring pyrimidine derivative and one of the four nucleobases in the nucleic acid of RNA. | ||||||||||||||||||||
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Uracil-d2 | 99.77% | Uracil-d2 is the deuterium labeled Uracil. Uracil is a common and naturally occurring pyrimidine derivative and one of the four nucleobases in the nucleic acid of RNA. | ||||||||||||||||||||
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Isocytosine | 99.62% | Isocytosine is a non-natural nucleobase and an isomer of cytosine. It is used in combination with Isoguanine in studies of unnatural nucleic acid analogues of the normal base pairs in DNA and used as a nucleobase of hachimoji RNA. | ||||||||||||||||||||
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1-Methylcytosine | 99.01% | 1-Methylcytosine is a pyrimidinone that serves as a nucleobase for hachimoji DNA and pairs with isoguanine. 1-Methylcytosine exerts weak antiproliferative activity against cervical cancer cells. 1-Methylcytosine can be used in the research of cervical cancer. | ||||||||||||||||||||
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5-Methylcytosine | 99.94% | 5-Methylcytosine is a well-characterized DNA modification in prokaryotes and eukaryotes. 5-Methylcytosine forms symmetrical methylation on CpG dinucleotides in DNA, stabilizes tRNA/rRNA structure in RNA, and affects mRNA translation. 5-Methylcytosine can be oxidized to generate 5hmC, 5fC, and 5caC. 5-Methylcytosine can be used in epigenetics, developmental biology, and the study of diseases such as colorectal cancer and hepatocellular carcinoma. | ||||||||||||||||||||
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5-Methylcytosine-d4 | 99% | 5-Methylcytosine-d4 is the deuterium labeled 5-Methylcytosine (HY-W008091). 5-Methylcytosine is a well-characterized DNA modification in prokaryotes and eukaryotes. 5-Methylcytosine forms symmetrical methylation on CpG dinucleotides in DNA, stabilizes tRNA/rRNA structure in RNA, and affects mRNA translation. 5-Methylcytosine can be oxidized to generate 5hmC, 5fC, and 5caC. 5-Methylcytosine can be used in epigenetics, developmental biology, and the study of diseases such as colorectal cancer and hepatocellular carcinoma. | ||||||||||||||||||||
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5-Bromocytosine | 99.77% | 5-Bromocytosine is a Cytosine (HY-I0626) derivative. 5-Bromocytosine can be incorporated into cellular DNA and promote DNA chain breakage and cross-linking under ultraviolet irradiation. | ||||||||||||||||||||
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5-Chloropyridin-3,4,6-d3-2-amine | 5-Chloropyridin-3,4,6-d3-2-amine is the deuterium labeled 5-Chloropyridin-2-amine. | |||||||||||||||||||||
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5-Azacytosine-15N4 | 5-Azacytosine-15N4 is the 15N labeled 5-Azacytosine (HY-Y0215). | |||||||||||||||||||||
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2-Amino-5-bromopyridine-d3 | 99.94% | 2-Amino-5-bromopyridine-d3 is the deuterium labeled 2-Amino-5-bromopyridine. | ||||||||||||||||||||
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References
- [1]. Maxam AM, et, al. A new method for sequencing DNA. Proc Natl Acad Sci U S A. 1977 Feb;74(2):560-4. [Content Brief]
- [2]. Oh G, et, al. Cytosine modifications exhibit circadian oscillations that are involved in epigenetic diversity and aging. Nat Commun. 2018 Feb 13;9(1):644. [Content Brief]
- [3]. Ngo TT, et al. Effects of cytosine modifications on DNA flexibility and nucleosome mechanical stability. Nat Commun. 2016 Feb 24;7:10813. [Content Brief]
- [4]. Warnecke PM, et al. Cytosine methylation and human cancer. Curr Opin Oncol. 2000 Jan;12(1):68-73. [Content Brief]
