Demethoxypiplartine
Demethoxypiplartine is an amide alkaloids which can be isolated from Piper flaviflorum and Piper sarmentosum. Demethoxypiplartine has antifungal activity against Cryptococcus neoformans with the IC50 of 18.1 μg/mL.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 130263-10-4
- 分子式: C16H17NO4
- 分子量:287.31
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MCF7 | IC50 |
3.7 μM
Compound: 12
|
Antiproliferative activity in human MCF7 cells assessed as cell viability after 48 hrs by alamarBlue assay
Antiproliferative activity in human MCF7 cells assessed as cell viability after 48 hrs by alamarBlue assay
|
[PMID: 27689728] |
| WI-38 | EC50 |
22.9 μM
Compound: 10
|
Senolytic activity against non-senescent human WI38 cells assessed as reduction in cell viability by propidium iodide staining based flow cytometry
Senolytic activity against non-senescent human WI38 cells assessed as reduction in cell viability by propidium iodide staining based flow cytometry
|
[PMID: 29925484] |
| WI-38 | EC50 |
8.3 μM
Compound: 10
|
Senolytic activity against ionizing radiation induced human WI38 senescent cells assessed as reduction in cell viability by propidium iodide staining based flow cytometry
Senolytic activity against ionizing radiation induced human WI38 senescent cells assessed as reduction in cell viability by propidium iodide staining based flow cytometry
|
[PMID: 29925484] |
化学情報
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CAS 番号 130263-10-4
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分子量 287.31
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分子式 C16H17NO4
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SMILES
O=C1C=CCCN1C(/C=C/C2=CC=C(OC)C(OC)=C2)=O
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)