(E)-JP-2-196 TFA
Based on 1 Customer Validation
JP-2-196 (TFA) is a molecular glue handle that can bind to the E3-ubiquitin ligases (RNF126, LRSAM1, RNF40, MID2, and RNF14) in vitro. JP-2-196 (TFA) can be used to synthesize molecular glue degraders.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 97.89%
- CAS 番号: 3065021-33-9
- 分子式: C17H19F3N2O5
- 分子量:388.34
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保管条件:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 1 year; -20°C, 6 months (sealed storage, away from moisture)
E3 Ligase Ligand-Linker Conjugates アイソフォーム固有の製品をすべて表示
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生物活性
化学情報
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CAS 番号 3065021-33-9
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性状 Solid
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分子量 388.34
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分子式 C17H19F3N2O5
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Color Light yellow to yellow
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SMILES
OC(C(F)(F)F)=O.O=C(N1CCNCC1)/C=C/C(C2=CC=C(C=C2)OC)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, sealed storage, away from moisture
* In solvent : -80°C, 1 year; -20°C, 6 months (sealed storage, away from moisture)
溶剤 & 溶解度
DMSO : 100 mg/mL (257.51 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months (sealed storage, away from moisture). When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months (sealed storage, away from moisture). When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (269 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months (sealed storage, away from moisture). When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.5751 mL | 12.8753 mL | 25.7506 mL | 64.3766 mL |
| 5 mM | 0.5150 mL | 2.5751 mL | 5.1501 mL | 12.8753 mL | |
| 10 mM | 0.2575 mL | 1.2875 mL | 2.5751 mL | 6.4377 mL | |
| 15 mM | 0.1717 mL | 0.8584 mL | 1.7167 mL | 4.2918 mL | |
| 20 mM | 0.1288 mL | 0.6438 mL | 1.2875 mL | 3.2188 mL | |
| 25 mM | 0.1030 mL | 0.5150 mL | 1.0300 mL | 2.5751 mL | |
| 30 mM | 0.0858 mL | 0.4292 mL | 0.8584 mL | 2.1459 mL | |
| 40 mM | 0.0644 mL | 0.3219 mL | 0.6438 mL | 1.6094 mL | |
| 50 mM | 0.0515 mL | 0.2575 mL | 0.5150 mL | 1.2875 mL | |
| 60 mM | 0.0429 mL | 0.2146 mL | 0.4292 mL | 1.0729 mL | |
| 80 mM | 0.0322 mL | 0.1609 mL | 0.3219 mL | 0.8047 mL | |
| 100 mM | 0.0258 mL | 0.1288 mL | 0.2575 mL | 0.6438 mL |