EBOV-IN-5
EBOV-IN-5 (compound 14) is an antiviral agent that inhibits Ebola virus (EBOV) infection. EBOV-IN-5 inhibits the binding of the EBOV glycoprotein EBOV-GPcl to NPC1, an indispensable host receptor required for viral fusion/entry.
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- CAS 番号: 68207-15-8
- 分子式: C18H21ClN4O3S
- 分子量:408.90
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
Ebola virus[1]
EBOV-IN-5 (compound 14) has a CC50 of 30 μM on HeLa cells and low cytotoxicity on Vero cells with a CC50 >100 μM[1].
EBOV-IN-5 (50 μM) significantly interferes with EBOV - GPcl/NPC1 interaction, IC50 against EBOV-GP-pseudotyped virus (pEBOV) is 4.69 μM[1].
EBOV-IN-5 IC50 against African swine fever virus ASFV is 35.17 μM[1].br /
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 68207-15-8
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分子量 408.90
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分子式 C18H21ClN4O3S
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SMILES
O=C(CN(CC)CC)NNC1=C(SC2=CC(Cl)=CC=C2[N+]([O-])=O)C=CC=C1
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
EBOV-IN-5 関連分類
HY-160880 関連分類
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