Ethyl maltol-d5
Based on 1 Customer Validation
Ethyl maltol-d5 is the deuterium labeled Ethyl maltol. Ethyl maltol (2-Ethyl-3-hydroxy-4H-pyran-4-one) is an orally active and important food additive and flavor enhancer. Ethyl maltol is less toxic to rats and dogs. Ethyl maltol can enhance copper-mediated cytotoxicity and induce apoptosis in lung epithelial cells.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.0%
- 分子式: C7H3D5O3
- 分子量:145.17
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保管条件:
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
生物活性
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
化学情報
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非標識Cas 4940-11-8
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性状 Solid
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分子量 145.17
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分子式 C7H3D5O3
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Color White to off-white
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SMILES
O=C1C=COC(C([2H])(C([2H])([2H])[2H])[2H])=C1O
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別名
2-Ethyl-3-hydroxy-4H-pyran-4-one-d5
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
溶剤 & 溶解度
DMSO : 100 mg/mL (688.85 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (277 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Niu Y, et al. Characterization of odor-active compounds of various cherry wines by gas chromatography-mass spectrometry, gas chromatography-olfactometry and their correlation with sensory attributes. J Chromatogr B Analyt Technol Biomed Life Sci. 2011 Aug 1;879(23):2287-93. [Content Brief]
[3]. Li Z, et al. Toxicity Studies of Ethyl Maltol and Iron Complexes in Mice.Biomed Res Int. 2017;2017:2640619. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 6.8885 mL | 34.4424 mL | 68.8848 mL | 172.2119 mL |
| 5 mM | 1.3777 mL | 6.8885 mL | 13.7770 mL | 34.4424 mL | |
| 10 mM | 0.6888 mL | 3.4442 mL | 6.8885 mL | 17.2212 mL | |
| 15 mM | 0.4592 mL | 2.2962 mL | 4.5923 mL | 11.4808 mL | |
| 20 mM | 0.3444 mL | 1.7221 mL | 3.4442 mL | 8.6106 mL | |
| 25 mM | 0.2755 mL | 1.3777 mL | 2.7554 mL | 6.8885 mL | |
| 30 mM | 0.2296 mL | 1.1481 mL | 2.2962 mL | 5.7404 mL | |
| 40 mM | 0.1722 mL | 0.8611 mL | 1.7221 mL | 4.3053 mL | |
| 50 mM | 0.1378 mL | 0.6888 mL | 1.3777 mL | 3.4442 mL | |
| 60 mM | 0.1148 mL | 0.5740 mL | 1.1481 mL | 2.8702 mL | |
| 80 mM | 0.0861 mL | 0.4305 mL | 0.8611 mL | 2.1526 mL | |
| 100 mM | 0.0689 mL | 0.3444 mL | 0.6888 mL | 1.7221 mL |