Alad - aminolevulinate, delta-, dehydratase Gene

Also Known as Lv; ALADH

生物種: Mus musculus

遺伝子タイプ: protein coding
遺伝子ID: 17025

Summary

Enables identical protein binding activity and porphobilinogen synthase activity. Acts upstream of or within cellular response to interleukin-4 and heme biosynthetic process. Predicted to be located in extracellular space. Predicted to be active in cytosol. Is expressed in several structures, including liver; lung; metanephros; spleen; and yolk sac. Human ortholog(s) of this gene implicated in porphyria cutanea tarda and sickle cell anemia. Orthologous to human ALAD (aminolevulinate dehydratase). [provided by Alliance of Genome Resources, Apr 2022]

Alad Products (2)

mRNA Protein Name
NM_001276446.1 NP_001263375.1 delta-aminolevulinic acid dehydratase
NM_008525.4 NP_032551.3 delta-aminolevulinic acid dehydratase

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence 参考文献 由来
enables porphobilinogen synthase activity IDA
IDA: Inferred from direct assay
4959158 MGI
enables porphobilinogen synthase activity IMP
IMP: Inferred from mutant phenotype
5393940 MGI
Biological Process GO Annotation Evidence 参考文献 由来
acts upstream of or within cellular response to interleukin-4 IDA
IDA: Inferred from direct assay
9798653 MGI
involved in heme A biosynthetic process IDA
IDA: Inferred from direct assay
14050799 MGI
involved in heme A biosynthetic process IMP
IMP: Inferred from mutant phenotype
5393940 MGI
involved in heme B biosynthetic process IDA
IDA: Inferred from direct assay
14050799 MGI
involved in heme B biosynthetic process IMP
IMP: Inferred from mutant phenotype
5393940 MGI
involved in heme O biosynthetic process IDA
IDA: Inferred from direct assay
14050799 MGI
involved in heme O biosynthetic process IMP
IMP: Inferred from mutant phenotype
5393940 MGI
acts upstream of or within heme biosynthetic process IDA
IDA: Inferred from direct assay
4959158 MGI
Cellular Component GO Annotation Evidence 参考文献 由来
is active in cytosol IDA
IDA: Inferred from direct assay
4981581 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

delta-aminolevulinic acid dehydratase

  • porphobilinogen synthase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS00553 ALAD Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17104 Alad Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23548 Alad Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Homo sapiens Alad NCBI NCBI:210