Tcn2 - transcobalamin 2 Gene

Also Known as Tcn-2

生物種: Mus musculus

遺伝子タイプ: protein coding
遺伝子ID: 21452

Summary

Predicted to enable cobalamin binding activity. Predicted to be involved in cobalamin transport. Predicted to act upstream of or within cobalt ion transport. Located in extracellular space. Is expressed in eye and genitourinary system. Human ortholog(s) of this gene implicated in Parkinson's disease; megaloblastic anemia; and transcobalamin II deficiency. Orthologous to human TCN2 (transcobalamin 2). [provided by Alliance of Genome Resources, Apr 2022]

Tcn2 Products (3)

mRNA Protein Name
NM_001130458.1 NP_001123930.1 transcobalamin-2 precursor
NM_001130459.1 NP_001123931.1 transcobalamin-2 precursor
NM_015749.3 NP_056564.1 transcobalamin-2 precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence 参考文献 由来
enables cargo receptor ligand activity IDA
IDA: Inferred from direct assay
237480 MGI
enables cobalamin binding IDA
IDA: Inferred from direct assay
21655200 MGI
enables molecular carrier activity IDA
IDA: Inferred from direct assay
21655200 MGI
Biological Process GO Annotation Evidence 参考文献 由来
involved in cobalamin transport IDA
IDA: Inferred from direct assay
237480 MGI
Cellular Component GO Annotation Evidence 参考文献 由来
is active in external side of plasma membrane IDA
IDA: Inferred from direct assay
237480 MGI
is active in extracellular space IDA
IDA: Inferred from direct assay
21655200 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

transcobalamin-2

  • TC II

  • TC-2

  • TCII

  • transcobalamin II

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS14319 TCN2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19166 Tcn2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25655 Tcn2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Homo sapiens Tcn2 NCBI NCBI:6948