Prdm6 - PR domain containing 6 Gene

Also Known as Gm92; PRISM

生物種: Mus musculus

遺伝子タイプ: protein coding
遺伝子ID: 225518

Summary

Enables identical protein binding activity. Acts upstream of or within negative regulation of smooth muscle cell differentiation; negative regulation of transcription, DNA-templated; and neurogenesis. Located in nucleus. Is expressed in several structures, including arterial system; central nervous system; genitourinary system; heart; and respiratory system. Human ortholog(s) of this gene implicated in patent ductus arteriosus. Orthologous to human PRDM6 (PR/SET domain 6). [provided by Alliance of Genome Resources, Apr 2022]

Prdm6 Products (1)

mRNA Protein Name
NM_001033281.3 NP_001028453.1 putative histone-lysine N-methyltransferase PRDM6
Molecular Function GO Annotation Evidence 参考文献 由来
enables identical protein binding IPI
IPI: Inferred from physical interaction
16537907 MGI
Biological Process GO Annotation Evidence 参考文献 由来
acts upstream of or within negative regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
16537907 MGI
acts upstream of or within negative regulation of smooth muscle cell differentiation IMP
IMP: Inferred from mutant phenotype
16537907 MGI
acts upstream of or within neurogenesis IDA
IDA: Inferred from direct assay
19050759 MGI
Cellular Component GO Annotation Evidence 参考文献 由来
located in nucleus IDA
IDA: Inferred from direct assay
16537907 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

putative histone-lysine N-methyltransferase PRDM6

  • PR domain-containing protein 6

  • PR domain-containing protein in smooth muscle

  • PR-domain zinc finger protein 6

Orthologs Information

生物種 Symbol 由来 ID
Homo sapiens Prdm6 NCBI NCBI:93166