Mcoln1 - mucolipin TRP cation channel 1 Gene

生物種: Rattus norvegicus

遺伝子タイプ: protein coding
遺伝子ID: 288371

Summary

Enables NAADP-sensitive calcium-release channel activity. Involved in release of sequestered calcium ion into cytosol. Located in lysosomal membrane. Human ortholog(s) of this gene implicated in glycoproteinosis and mucolipidosis type IV. Orthologous to human MCOLN1 (mucolipin TRP cation channel 1). [provided by Alliance of Genome Resources, Apr 2022]

Mcoln1 Products (1)

mRNA Protein Name
NM_001105903.1 NP_001099373.1 mucolipin-1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence 参考文献 由来
enables NAADP-sensitive calcium-release channel activity IDA
IDA: Inferred from direct assay
17613490 RGD
Biological Process GO Annotation Evidence 参考文献 由来
involved in release of sequestered calcium ion into cytosol IDA
IDA: Inferred from direct assay
17613490 RGD
Cellular Component GO Annotation Evidence 参考文献 由来
located in lysosomal membrane IDA
IDA: Inferred from direct assay
17613490 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

mucolipin-1

  • mucolipin 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS08244 MCOLN1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20178 Mcoln1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26682 Mcoln1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Homo sapiens Mcoln1 NCBI NCBI:57192