Pkp1 - plakophilin 1 Gene

Predicted to enable Cadherin binding activity and lamin binding activity. Predicted to be involved in several processes, including cell-cell junction assembly; intermediate filament bundle assembly; and negative regulation of mRNA catabolic process. Predicted to be located in desmosome and nucleoplasm. Predicted to be part of messenger ribonucleoprotein complex. Predicted to be active in several cellular components, including adherens junction; nucleus; and plasma membrane. Human ortholog(s) of this gene implicated in ectodermal dysplasia. Orthologous to human PKP1 (plakophilin 1). [provided by Alliance of Genome Resources, Apr 2022]