Ccbe1 - collagen and calcium binding EGF domains 1 Gene

Also Known as mKIAA1983; 4933426F18Rik; 9430093N24Rik

生物種: Mus musculus

遺伝子タイプ: protein coding
遺伝子ID: 320924

Summary

Predicted to enable Collagen binding activity and protease binding activity. Involved in positive regulation of angiogenesis and positive regulation of lymphangiogenesis. Acts upstream of or within several processes, including lymphangiogenesis; positive regulation of endothelial cell migration; and respiratory system process. Predicted to be located in extracellular matrix and extracellular space. Predicted to be part of Collagen trimer. Is expressed in several structures, including anterior cardinal vein; branchial arch; embryo mesenchyme; heart; and intraembryonic coelom. Human ortholog(s) of this gene implicated in Hennekam syndrome. Orthologous to human CCBE1 (Collagen and calcium binding EGF domains 1). [provided by Alliance of Genome Resources, Apr 2022]

Ccbe1 Products (1)

mRNA Protein Name
NM_178793.4 NP_848908.1 collagen and calcium-binding EGF domain-containing protein 1 precursor
Biological Process GO Annotation Evidence 参考文献 由来
acts upstream of endothelial cell migration IMP
IMP: Inferred from mutant phenotype
21778431 MGI
acts upstream of or within lung development IMP
IMP: Inferred from mutant phenotype
24733830 MGI
acts upstream of or within lymph vessel development IMP
IMP: Inferred from mutant phenotype
24733830 MGI
acts upstream of or within lymphangiogenesis IMP
IMP: Inferred from mutant phenotype
21778431 MGI
acts upstream of lymphatic endothelial cell migration IMP
IMP: Inferred from mutant phenotype
21778431 MGI
involved in positive regulation of angiogenesis IDA
IDA: Inferred from direct assay
24552833 MGI
acts upstream of or within positive regulation of endothelial cell migration IMP
IMP: Inferred from mutant phenotype
21778431 MGI
involved in positive regulation of lymphangiogenesis IDA
IDA: Inferred from direct assay
24552833 MGI
acts upstream of or within respiratory gaseous exchange by respiratory system IMP
IMP: Inferred from mutant phenotype
24733830 MGI
acts upstream of or within respiratory system process IMP
IMP: Inferred from mutant phenotype
24733830 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

collagen and calcium-binding EGF domain-containing protein 1

  • full of fluid protein homolog

Orthologs Information

生物種 Symbol 由来 ID
Homo sapiens Ccbe1 NCBI NCBI:147372