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SNAI3 - snail family transcriptional repressor 3 Gene

Also Known as SMUC; SNAIL3; ZNF293; Zfp293

生物種: Homo sapiens

遺伝子タイプ: protein coding

遺伝子ID: 333929

About SNAI3

Cytogenetic location: 16q24.2 Genomic coordinates (GRCh38): 16:88,677,688-88,686,507 (from NCBI)

This gene has 1 transcript (splice variant), 141 orthologues and 36 paralogues. Broad expression in lymph node (RPKM 1.8), spleen (RPKM 1.7) and 25 other tissues.

Summary

SNAI3 is a member of the SNAIL gene family, named for the Drosophila snail gene, which plays roles in mesodermal formation during embryogenesis (Katoh and Katoh, 2003 [PubMed 12579345]).[supplied by OMIM, Apr 2009]

SNAI3 Products (1)

mRNA	Protein	Name
NM_178310.4	NP_840101.1	zinc finger protein SNAI3

Gene Ontology

Molecular Function

Molecular Function GO Annotation	Evidence	参考文献	由来
enables sequence-specific double-stranded DNA binding	IDA IDA: Inferred from direct assay	28473536	GOA

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SNAI3 Protein Structure

zf-C2H2

zf-H2C2_2

zf-C2H2

0
100
200
292 a.a.

Protein Preferred Names	Protein Names
zinc finger protein SNAI3	protein snail homolog 3

関連疾患

Diseases	Alias
Parkinson Disease 7, Autosomal Recessive Early-Onset	Autosomal Recessive Early-Onset Parkinson Disease 7 PARK7 Parkinson'S Disease 7 Autosomal Recessive Early-Onset Parkinson'S Disease 7 Parkinson Disease 7 Amyotrophic Lateral Sclerosis-Parkinsonism/Dementia Complex Type 2 Autosomal Recessive Early-Onset Parkinson Disease Type 7 Parkinson Disease, Type 7
Waardenburg Syndrome, Type 2e	Waardenburg Syndrome Type 2 Waardenburg Syndrome Type 2e WS2E Waardenburg Syndrome, Type 2e, With Or Without Neurologic Involvement Waardenburg Syndrome, Type Iie Hypogonadotropic Hypogonadism With Anosmia And Deafness With Or Without Hypopigmentation Waardenburg Syndrome Type 2e With Or Without Neurologic Involvement Waardenburg Syndrome Type Iie Hypogonadotropic Hypogonadism With Anosmia And Deafness, With Or Without Hypopigmentation Ws2e, With Or Without Neurologic Involvement Ws2e With Or Without Neurological Involvement Ws 2 Ws Type 2 Ws2 Waardenburg Syndrome Type Ii Waardenburg Syndrome 2e Kallmann Syndrome And Deafness With Or Without Hypopigmentation Ws2e With Or Without Neurologic Involvement Waardenburg Syndrome Type 2e, Without Neurologic Involvement Ws-2

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)

製品番号	製品名	製品効果	純度	Rare Diseases
HY-RS13472	SNAI3 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

生物種	Symbol	由来	ID
Bos taurus	SNAI3	VGNC	VGNC:35049
Rattus norvegicus	SNAI3	RGD	RGD:1309658
Mus musculus	SNAI3	MGD	MGI:1353563
Canis familiaris	SNAI3	VGNC	VGNC:46586
Macaca mulatta	SNAI3	VGNC	VGNC:77735
Others	SNAI3	NCBI