ST8SIA6 - ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 Gene

Also Known as SIA8F; SIAT8F; SIAT8-F; ST8SiaVI; ST8SIA-VI

生物種: Homo sapiens

遺伝子タイプ: protein coding
遺伝子ID: 338596

About ST8SIA6

Cytogenetic location: 10p12.33 Genomic coordinates (GRCh38): 10:17,315,421-17,454,595 (from NCBI)

This gene has 3 transcripts (splice variants), 125 orthologues and 5 paralogues. Broad expression in lung (RPKM 3.3), heart (RPKM 1.0) and 14 other tissues.

Summary

This gene encodes a member of the Glycosyltransferase 29 protein family. Members of this protein family synthesize sialylglycoconjugates. Sialylation may contribute to multidrug resistance in Cancer cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]

ST8SIA6 Products (2)

mRNA Protein Name
NM_001004470.3 NP_001004470.1 alpha-2,8-sialyltransferase 8F isoform 1 precursor
NM_001345961.2 NP_001332890.1 alpha-2,8-sialyltransferase 8F isoform 2

ST8SIA6 Protein Structure

Glyco_transf_29

Glyco_transf_29: Glycosyltransferase family 29 (sialyltransferase) (135 - 392)

  • 0
  • 100
  • 200
  • 300
  • 398 a.a.
Protein Preferred Names Protein Names

alpha-2,8-sialyltransferase 8F

  • ST8 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase 6

関連疾患

Diseases Alias
Lice Infestation
  • Pediculosis

  • Louse Infestation

  • Mixed Pediculosis

  • Lice Infestations

  • Infestation By Pediculus

  • Mixed Pediculosis Infestation

  • Pediculosis + Lice

  • Pediculosis And Phthirus Infection

  • Pediculosis And Phthirus Infections

  • Pediculosis And Phthirus Infestation

  • Infestation By Anoplura

  • Pediculus Infestation

  • Lice Nos

Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

生物種 Symbol 由来 ID
Mus musculus ST8SIA6 MGD MGI:2386797
Rattus norvegicus ST8SIA6 RGD RGD:1303161
Bos taurus ST8SIA6 VGNC VGNC:35347
Canis familiaris ST8SIA6 VGNC VGNC:46868