Nr1h2 - nuclear receptor subfamily 1, group H, member 2 Gene

Also Known as LXRB; OR-1; LXRbeta; LXR beta

生物種: Rattus norvegicus

遺伝子タイプ: protein coding
遺伝子ID: 58851

Summary

Enables DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and retinoid X receptor binding activity. Contributes to sequence-specific DNA binding activity. Involved in regulation of gene expression; response to nutrient levels; and retinoic acid receptor signaling pathway. Predicted to be located in cytoplasm and nucleus. Biomarker of obesity. Human ortholog(s) of this gene implicated in obesity and type 2 diabetes mellitus. Orthologous to human NR1H2 (nuclear receptor subfamily 1 group H member 2). [provided by Alliance of Genome Resources, Apr 2022]

Nr1h2 Products (4)

mRNA Protein Name
NM_001398609.1 NP_001385538.1 oxysterols receptor LXR-beta isoform a
NM_001398610.1 NP_001385539.1 oxysterols receptor LXR-beta isoform a
NM_001398611.1 NP_001385540.1 oxysterols receptor LXR-beta isoform b
NM_031626.3 NP_113814.2 oxysterols receptor LXR-beta isoform b
Protein Preferred Names Protein Names

oxysterols receptor LXR-beta

  • UR

  • liver X receptor beta

  • nuclear orphan receptor LXR-beta

  • orphan nuclear receptor OR-1

  • ubiquitous receptor

  • ubiquitously-expressed nuclear receptor

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS09529 NR1H2 Human Pre-designed siRNA Set A / Unkown
HY-RS19726 Nr1h2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26222 Nr1h2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Homo sapiens Nr1h2 NCBI NCBI:7376