NFATC2IP - nuclear factor of activated T cells 2 interacting protein Gene

Also Known as ESC2; NIP45; RAD60

生物種: Homo sapiens

遺伝子タイプ: protein coding
遺伝子ID: 84901

About NFATC2IP

Cytogenetic location: 16p11.2 Genomic coordinates (GRCh38): 16:28,950,937-28,967,092 (from NCBI)

This gene has 7 transcripts (splice variants), 153 orthologues and 3 paralogues. Ubiquitous expression in lymph node (RPKM 11.4), spleen (RPKM 10.6) and 25 other tissues.

Summary

Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2022]

NFATC2IP Products (4)

mRNA Protein Name
NM_001394784.1 NP_001381713.1 NFATC2-interacting protein isoform 2
NM_001394785.1 NP_001381714.1 NFATC2-interacting protein isoform 3
NM_001394786.1 NP_001381715.1 NFATC2-interacting protein isoform 4
NM_032815.4 NP_116204.3 NFATC2-interacting protein isoform 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence 参考文献 由来
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

NFATC2IP Protein Structure

Rad60-SLD

Rad60-SLD: Ubiquitin-2 like Rad60 SUMO-like (349 - 417)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 419 a.a.
Protein Preferred Names Protein Names

NFATC2-interacting protein

  • 45 kDa NF-AT-interacting protein

関連疾患

Diseases Alias
Tuberculous Empyema

  • Empyema, Tuberculous

  • Empyema Tuberculous
Cone-Rod Dystrophy 1

  • CORD1

  • Crd1

  • Cone-Rod Retinal Dystrophy-1

  • Retinitis Pigmentosa 1
Vitreous Detachment

  • Posterior Vitreous Detachment

  • Vitreous Syneresis
Cone-Rod Dystrophy 2

  • Cone-Rod Dystrophy

  • CORD2

  • Cone-Rod Retinal Dystrophy

  • Rcrd2

  • Cone-Rod Retinal Dystrophy 2

  • Crd2

  • Cord

  • Crd

  • Retinal Cone-Rod Dystrophy

  • Cone-Rod Retinal Dystrophy-2

  • Retinal Cone-Rod Dystrophy 2

  • Tapetoretinal Degeneration

  • Cone-Rod Degeneration

  • Cone Rod Dystrophy

  • Dystrophy, Cone-Rod

  • Dystrophy, Cone-Rod, Type 2

  • Retinitis Pigmentosa

  • Retinitis Pigmentosa 2

  • Progressive Cone-Rod Dystrophy
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS09240 NFATC2IP Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Felis catus NFATC2IP VGNC VGNC:63789
Rattus norvegicus NFATC2IP RGD RGD:1359096
Canis familiaris NFATC2IP VGNC VGNC:43768
Bos taurus NFATC2IP VGNC VGNC:32032
Mus musculus NFATC2IP MGD MGI:1329015
Macaca mulatta NFATC2IP VGNC VGNC:75261
Others NFATC2IP NCBI