SYTL3 - synaptotagmin like 3 Gene

Also Known as SLP3

生物種: Homo sapiens

遺伝子タイプ: protein coding
遺伝子ID: 94120

About SYTL3

This gene has 4 transcripts (splice variants), 157 orthologues and 31 paralogues. Ubiquitous expression in thyroid (RPKM 15.0), small intestine (RPKM 10.0) and 25 other tissues.

Summary

The protein encoded by this gene belongs to a family of peripheral membrane proteins that play a role in vesicular trafficking. This protein binds Phospholipids in the presence of calcium ions. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2016]

SYTL3 Products (5)

mRNA Protein Name
NM_001009991.4 NP_001009991.2 synaptotagmin-like protein 3 isoform 2
NM_001242384.2 NP_001229313.1 synaptotagmin-like protein 3 isoform 1
NM_001242394.2 NP_001229323.1 synaptotagmin-like protein 3 isoform 1
NM_001242395.2 NP_001229324.1 synaptotagmin-like protein 3 isoform 2
NM_001318745.2 NP_001305674.1 synaptotagmin-like protein 3 isoform 3

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence 参考文献 由来
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

SYTL3 Protein Structure

FYVE_2

FYVE_2: FYVE-type zinc finger (9 - 123)

C2

C2: C2 domain (323 - 411)

C2

C2: C2 domain (483 - 568)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 610 a.a.
Protein Preferred Names Protein Names

synaptotagmin-like protein 3

  • exophilin-6

SYTL3 Protein-protein interaction Information

Type
タンパク質名 Protein ID Interactor Interactor Species Interactor ID Detection Method 参考文献
Intra
SYTL3 Q4VX76 ANKRD11 Homo sapiens X5D778
Validated Y2H
32296183
Cross: Cross-species interaction Intra: Intraspecies interaction

関連疾患

Diseases Alias
Griscelli Syndrome

  • Chediak-Higashi-Like Syndrome

  • Griscelli-Prunieras Syndrome

  • Partial Albinism-Immunodeficiency Syndrome

  • Griscelli Disease

  • Gs

  • Hypopigmentation Immunodeficiency Disease

  • Partial Albinism With Immunodeficiency

  • Immunodeficiency Syndrome With Hypopigmentation

  • Hypopigmentation-Immunodeficiency Disease
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
製品番号 製品名
製品効果
純度
Rare Diseases
HY-RS14124 SYTL3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

生物種 Symbol 由来 ID
Canis familiaris SYTL3 VGNC VGNC:47052
Bos taurus SYTL3 VGNC VGNC:35547
Mus musculus SYTL3 MGD MGI:1933367
Felis catus SYTL3 VGNC VGNC:65906
Rattus norvegicus SYTL3 RGD RGD:1561992
Macaca mulatta SYTL3 VGNC VGNC:104431
Others SYTL3 NCBI