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製品番号: HY-184361

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Juniperonic acid ethyl ester

(別名: Ethyl 20:4BSO)

Juniperonic acid ethyl ester (Ethyl 20:4BSO) is an orally active non-methylene-interrupted ω-3 polyunsaturated fatty acid ethyl ester. Juniperonic acid ethyl ester exists in Platycladus orientalis seed oil. Juniperonic acid ethyl ester reduces the ratio of 20:3n-9 to arachidonic acid in hepatic phosphatidylcholine of rats with essential fatty acid deficiency. Juniperonic acid ethyl ester is applicable to the research of hypertension and hepatic reperfusion injury.

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CAS 番号: 143202-57-7
分子式: C₂₂H₃₆O₂
分子量:332.53

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Juniperonic acid ethyl ester 構造式

CAS 番号: 143202-57-7

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生物活性

製品説明

体内実験

Juniperonic acid ethyl ester (100 mg/day; p.o.; daily; 10 days) reduces the 20:3n-9/AA ratio in liver PC of essential fatty acid-deficient rats to 1.8, demonstrating essential fatty acid activity comparable to that of α-linolenic acid and γ-linolenic acid^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:

Sprague-Dawley (male, 3-wk-old at study start, essential fatty acid deficiency induced via 66 days of fat-free diet)^[1]
Dosage:

100 mg/day
Administration:

p.o.; daily; 3 days, 10 days
Result:

Reduced the ratio of 20:3n-9 to arachidonic acid (AA) in liver phosphatidylcholine (PC) to 1.8 after 10 days of administration.
Achieved a proportion of AA in liver PC of 6.7% after 10 days of administration.
Achieved a proportion of 20:3n-9 in liver PC of 12.0% after 10 days of administration.

化学情報

CAS 番号 143202-57-7
分子量 332.53
分子式 C₂₂H₃₆O₂
SMILES

C(=C\CCCC/C=C\C/C=C\C/C=C\CC)\CCCC(OCC)=O
別名

Ethyl 20:4BSO
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

取扱説明書 (2659 KB)

参考文献

[1]. Ikeda I, et al. 5c,11c,14c-eicosatrienoic acid and 5c,11c,14c,17c-eicosatetraenoic acid of Biota orientalis seed oil affect lipid metabolism in the rat. Lipids. 1992 Jul;27(7):500-4. [Content Brief]

[2]. Montañés F, et al. Isolation of non-methylene interrupted or acetylenic fatty acids from seed oils using semi-preparative supercritical chromatography[J]. Journal of the American Oil Chemists' Society, 2017, 94(7): 981-991.

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Juniperonic acid ethyl ester

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Juniperonic acid ethyl ester

生物活性

化学情報

純度とドキュメンテーション

参考文献

Calculators

Help & FAQs

Juniperonic acid ethyl ester 関連分類

HY-184361 関連分類