LEB-03-146
Based on 1 Customer Validation
LEB-03-146 is a WEE1 DUBTAC (deubiquitinase-targeting chimera) linking AZD1775 (Adavosertib) to the OTUB1 recruiter EN523 through a PEG2 linker. LEB-03-146 shows significant WEE1 stabilization in HEP3B hepatoma cancer cells.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.08%
- CAS 番号: 2858812-91-4
- 分子式: C46H57N11O8
- 分子量:892.01
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保管条件:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
化学情報
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CAS 番号 2858812-91-4
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性状 Solid
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分子量 892.01
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分子式 C46H57N11O8
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Color Light yellow to yellow
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SMILES
C=CCN1C(C2=C(N1C3=NC(C(C)(O)C)=CC=C3)N=C(N=C2)NC4=CC=C(C=C4)N5CCN(CC5)CCOCCOCCNC(CCC6=CC=C(O6)N7CCN(CC7=O)C(C=C)=O)=O)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : ≥ 50 mg/mL (56.05 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (265 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.1211 mL | 5.6053 mL | 11.2106 mL | 28.0266 mL |
| 5 mM | 0.2242 mL | 1.1211 mL | 2.2421 mL | 5.6053 mL | |
| 10 mM | 0.1121 mL | 0.5605 mL | 1.1211 mL | 2.8027 mL | |
| 15 mM | 0.0747 mL | 0.3737 mL | 0.7474 mL | 1.8684 mL | |
| 20 mM | 0.0561 mL | 0.2803 mL | 0.5605 mL | 1.4013 mL | |
| 25 mM | 0.0448 mL | 0.2242 mL | 0.4484 mL | 1.1211 mL | |
| 30 mM | 0.0374 mL | 0.1868 mL | 0.3737 mL | 0.9342 mL | |
| 40 mM | 0.0280 mL | 0.1401 mL | 0.2803 mL | 0.7007 mL | |
| 50 mM | 0.0224 mL | 0.1121 mL | 0.2242 mL | 0.5605 mL |
LEB-03-146 関連分類
HY-144999 関連分類
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