Spermine NONOate
Based on 2 publication(s) in Google Scholar
Spermine NONOate is a complex of nitric oxide (NO) with spermine and acts as a NO donor. Spermine NONOate can be used for NO aqueous solutions preparing.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.07%
- CAS 番号: 136587-13-8
- 分子式: C10H26N6O2
- 分子量:262.35
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保管条件:
-80°C, protect from light, stored under nitrogen
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
MedChemExpress（MCE）の使用を引用している文献 Spermine NONOate
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生物活性
Spermine NONOate has a half-life of 39 minutes and 230 minutes at 37°C and 22-25°C, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 136587-13-8
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性状 Solid
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分子量 262.35
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分子式 C10H26N6O2
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Color White to off-white
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SMILES
NCCCNCCCCN(CCCN)N(O)N=O
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輸送条件
Shipping with dry ice.
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保管条件
-80°C, protect from light, stored under nitrogen
Publications (2)
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Journal Impact Factor
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Most Recent
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Antioxidants (Basel)
2025 Mar 4;14(3):311. PMID: 40227269 -
Front Pharmacol
Long-term nitric oxide exposure induces cough hypersensitivity via non-inflammatory activation of the HIF1α-TRPV1 pathway. [Abstract]2026 Jan 19:17:1679727. PMID: 41635485
溶剤 & 溶解度
H2O : ≥ 100 mg/mL (381.17 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
For the following dissolution methods, please prepare the working solution directly:
It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: PBS
Solubility: 50 mg/mL (190.59 mM); Clear solution; Need ultrasonic
純度とドキュメンテーション
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データシート (268 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. A Ramamurthi , et al. Measurement and modeling of nitric oxide release rates for nitric oxide donors. Chem Res Toxicol. 1997 Apr;10(4):408-13. [Content Brief]
[2]. K Homer, et al. In vitro comparison of two NONOates (novel nitric oxide donors) on rat pulmonary arteries. Eur J Pharmacol. 1998 Aug 28;356(1):49-57. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 3.8117 mL | 19.0585 mL | 38.1170 mL | 95.2925 mL |
| 5 mM | 0.7623 mL | 3.8117 mL | 7.6234 mL | 19.0585 mL | |
| 10 mM | 0.3812 mL | 1.9059 mL | 3.8117 mL | 9.5293 mL | |
| 15 mM | 0.2541 mL | 1.2706 mL | 2.5411 mL | 6.3528 mL | |
| 20 mM | 0.1906 mL | 0.9529 mL | 1.9059 mL | 4.7646 mL | |
| 25 mM | 0.1525 mL | 0.7623 mL | 1.5247 mL | 3.8117 mL | |
| 30 mM | 0.1271 mL | 0.6353 mL | 1.2706 mL | 3.1764 mL | |
| 40 mM | 0.0953 mL | 0.4765 mL | 0.9529 mL | 2.3823 mL | |
| 50 mM | 0.0762 mL | 0.3812 mL | 0.7623 mL | 1.9059 mL | |
| 60 mM | 0.0635 mL | 0.3176 mL | 0.6353 mL | 1.5882 mL | |
| 80 mM | 0.0476 mL | 0.2382 mL | 0.4765 mL | 1.1912 mL | |
| 100 mM | 0.0381 mL | 0.1906 mL | 0.3812 mL | 0.9529 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
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