Z226407860
Z226407860 is a RING-box protein 1 (RBX1) inhibitor. Z226407860 reduces house dust mite-induced airway epithelial injury and ROS accumulation by inhibiting RBX1. Z226407860 can be used for the research of asthma.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 2419496-02-7
- 分子式: C28H36N4O5S
- 分子量:540.67
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
Z226407860 (5 μM) potently inhibits the expression of RBX1 mRNA and protein in normal HBE cells, and suppresses HDM-induced overexpression of RBX1 protein in HBE cells[1].
Z226407860 (5 μM) alleviates HDM-induced epithelial barrier dysfunction in HBE cells by restoring the levels of Occludin and E-cadherin, and reduces the accumulation of reactive oxygen species (ROS) in cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 2419496-02-7
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分子量 540.67
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分子式 C28H36N4O5S
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SMILES
OC1=CC=C(CCC2CCN(C(CCC3=NC(C=C(S(N4CCOCC4)(=O)=O)C=C5)=C5N3C)=O)CC2)C=C1
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Z226407860 関連分類
HY-182063 関連分類
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