Chlorpyrifos-d10
Based on 1 Customer Validation
Chlorpyrifos-d10 is the deuterium labeled Chlorpyrifos. Chlorpyrifos is an organophosphate insecticide that is classified as a phosphorothionate. The oxon metabolite of Chlorpyrifos is an inhibitor of acetylcholinesterase (AChE), affecting neurological function in insects, humans, and other animals. The Chlorpyrifos oxon (CPO) metabolite is hydrolyzed by the plasma enzyme paraoxonase 1 (PON1), and susceptibility to neurotoxicity associated with CPO exposure is mitigated by PON1 overexpression.
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- Purity: 99.49%
- CAS No.: 285138-81-0
- 화학식: C9HD10Cl3NO3PS
- 분자량:360.65
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보관:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 285138-81-0
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Unlabeled Cas 2921-88-2
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Appearance Solid
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분자량 360.65
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화학식 C9HD10Cl3NO3PS
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Color White to off-white
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SMILES
S=P(OC([2H])([2H])C([2H])([2H])[2H])(OC1=NC(Cl)=C(Cl)C=C1Cl)OC([2H])([2H])C([2H])([2H])[2H]
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
용액&용해도
H2O : 100 mg/mL (277.28 mM; Need ultrasonic)
DMSO : 50 mg/mL (138.64 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (278 KB)
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SDS (564 KB)
- English - EN (564 KB)
- Français - FR (564 KB)
- Deutsch - DE (564 KB)
- Norwegian - NO (564 KB)
- Español - ES (564 KB)
- Swedish - SV (564 KB)
- Italian - IT (564 KB)
- Korean - KR (564 KB)
- Portuguese - PT (564 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO / H2O | 1 mM | 2.7728 mL | 13.8639 mL | 27.7277 mL | 69.3193 mL |
| 5 mM | 0.5546 mL | 2.7728 mL | 5.5455 mL | 13.8639 mL | |
| 10 mM | 0.2773 mL | 1.3864 mL | 2.7728 mL | 6.9319 mL | |
| 15 mM | 0.1849 mL | 0.9243 mL | 1.8485 mL | 4.6213 mL | |
| 20 mM | 0.1386 mL | 0.6932 mL | 1.3864 mL | 3.4660 mL | |
| 25 mM | 0.1109 mL | 0.5546 mL | 1.1091 mL | 2.7728 mL | |
| 30 mM | 0.0924 mL | 0.4621 mL | 0.9243 mL | 2.3106 mL | |
| 40 mM | 0.0693 mL | 0.3466 mL | 0.6932 mL | 1.7330 mL | |
| 50 mM | 0.0555 mL | 0.2773 mL | 0.5546 mL | 1.3864 mL | |
| 60 mM | 0.0462 mL | 0.2311 mL | 0.4621 mL | 1.1553 mL | |
| 80 mM | 0.0347 mL | 0.1733 mL | 0.3466 mL | 0.8665 mL | |
| 100 mM | 0.0277 mL | 0.1386 mL | 0.2773 mL | 0.6932 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
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