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Cat. No.: HY-N1817

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Demethoxypiplartine

Demethoxypiplartine is an amide alkaloids which can be isolated from Piper flaviflorum and Piper sarmentosum. Demethoxypiplartine has antifungal activity against Cryptococcus neoformans with the IC₅₀ of 18.1 μg/mL.

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CAS No.: 130263-10-4
화학식: C₁₆H₁₇NO₄
분자량:287.31

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

Demethoxypiplartine Chemical Structure

CAS No.: 130263-10-4

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- Cellular Effect
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Bioz

Biological Activity

제품 설명

Cellular Effect

Cell Line	Type	Value	Description	References
MCF7	IC₅₀	3.7 μM Compound: 12	Antiproliferative activity in human MCF7 cells assessed as cell viability after 48 hrs by alamarBlue assay Antiproliferative activity in human MCF7 cells assessed as cell viability after 48 hrs by alamarBlue assay	[PMID: 27689728]
WI-38	EC₅₀	22.9 μM Compound: 10	Senolytic activity against non-senescent human WI38 cells assessed as reduction in cell viability by propidium iodide staining based flow cytometry Senolytic activity against non-senescent human WI38 cells assessed as reduction in cell viability by propidium iodide staining based flow cytometry	[PMID: 29925484]
WI-38	EC₅₀	8.3 μM Compound: 10	Senolytic activity against ionizing radiation induced human WI38 senescent cells assessed as reduction in cell viability by propidium iodide staining based flow cytometry Senolytic activity against ionizing radiation induced human WI38 senescent cells assessed as reduction in cell viability by propidium iodide staining based flow cytometry	[PMID: 29925484]

Chemical Information

CAS No. 130263-10-4
분자량 287.31
화학식 C₁₆H₁₇NO₄
SMILES

O=C1C=CCCN1C(/C=C/C2=CC=C(OC)C(OC)=C2)=O
Structure Classification
- Alkaloids
- Pyridine Alkaloids
Initial Source
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Shi YN, et al. Antifungal Amide Alkaloids from the Aerial Parts of Piper flaviflorum and Piper sarmentosum. Planta Med. 2017 Jan;83(1-02):143-150. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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