B4GALNT3 - beta-1,4-N-acetyl-galactosaminyltransferase 3 Gene
Species: Homo sapiens
Gene Type: protein coding
Gene ID: 283358
About B4GALNT3
Cytogenetic location: 12p13.33
Genomic coordinates (GRCh38): 12:459,939-563,509 (from NCBI)
This gene has 7 transcripts (splice variants), 198 orthologues and 7 paralogues. Biased expression in stomach (RPKM 33.1), colon (RPKM 16.3) and 11 other tissues.
Summary
B4GALNT3 transfers N-acetylgalactosamine (GalNAc) onto glucosyl residues to form N,N-prime-diacetyllactosediamine (LacdiNAc, or LDN), a unique terminal structure of cell surface N-glycans (Ikehara et al., 2006 [PubMed 16728562]).[supplied by OMIM, Aug 2008]
B4GALNT3 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_173593.4 | NP_775864.3 | beta-1,4-N-acetylgalactosaminyltransferase 3 |
B4GALNT3 Protein Structure
PA14
PA14: PA14 domain (130 - 275)
CHGN
CHGN: Chondroitin N-acetylgalactosaminyltransferase (672 - 983)
- 0
- 200
- 400
- 600
- 800
- 998 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
beta-1,4-N-acetylgalactosaminyltransferase 3 |
|
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Idiopathic Peripheral Autonomic Neuropathy |
|
|
| Chronic Polyneuropathy |
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
Bioactive Molecules
(1)
| Cat. No. | 상품명 |
효과
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS01317 | B4GALNT3 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
Orthologs Information
| Species | Symbol | Source | ID |
|---|---|---|---|
| Rattus norvegicus | B4GALNT3 | RGD | RGD:1561056 |
| Mus musculus | B4GALNT3 | MGD | MGI:3041155 |
| Macaca mulatta | B4GALNT3 | VGNC | VGNC:70121 |
| Felis catus | B4GALNT3 | VGNC | VGNC:60064 |
| Bos taurus | B4GALNT3 | VGNC | VGNC:26387 |
| Canis familiaris | B4GALNT3 | VGNC | VGNC:38347 |
| Others | B4GALNT3 | NCBI |
Compound Screening Libraries
Virtual Screening
Customize Your Library
Drug Screening Service