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NMDA receptor antagonist 11

NMDA receptor antagonist 11 is a NMDA receptor antagonist with an IC₅₀ of 65 μM. NMDA receptor antagonist 11 inhibits glycine action at the NMDA receptor glycine site. NMDA receptor antagonist 11 can be used for research on neurological diseases.

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CAS No.: 26727-26-4
화학식: C₆H₁₂N₂O₃
분자량:160.17

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

NMDA receptor antagonist 11 Chemical Structure

CAS No.: 26727-26-4

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
- Cellular Effect
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
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Biological Activity

제품 설명

IC₅₀ & Target^[1]

NMDA Receptor

65 μM (IC₅₀)

All iGluR Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
Oocyte	IC₅₀	65 μM Compound: 1	Activity at rat NR1/NR2A receptor expressed in Xenopus oocytes assessed as inhibition of glycine-induced electrophysiological response Activity at rat NR1/NR2A receptor expressed in Xenopus oocytes assessed as inhibition of glycine-induced electrophysiological response	[PMID: 19394821]

In Vitro

NMDA receptor antagonist 11 (Compound 1) exhibits an IC₅₀ of 65 μM against NMDA receptor glycine site^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 26727-26-4
분자량 160.17
화학식 C₆H₁₂N₂O₃
SMILES

O=C(CNC(CCCN)=O)O
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Nguyen KT, et al. 3-(aminomethyl)piperazine-2,5-dione as a novel NMDA glycine site inhibitor from the chemical universe database GDB. Bioorg Med Chem Lett. 2009;19(14):3832-3835. [Content Brief]

Calculators

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass

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Volume

Molecular Weight

농도 희석 계산기

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Concentration _(start)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- 제품 설명
- IC50 & Target
- In Vitro
Chemical Information
순도&문서
References

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