Escin IIb
Escin IIb, isolated from horse chestnut, the seeds of Aesculus hippocastanum L., has positive effects on acute inflammation in animals. Escin IIb showed potent protective effects against ethanol-induced gastric mucosal lesions.
For research use only. We do not sell to patients.
- CAS No.: 158800-83-0
- Formula: C54H84O23
- Molecular Weight:1101.23
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Escin IIb (10-50 mg/kg; p.o.) potently inhibits ethanol-induced gastric mucosal lesions[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Male Sprague–Dawley rats (Ethanol-induced gastric mucosal lesions in rats)[2]
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Dosage:P.o.
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Administration:10-50 mg/kg
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Result:Showed a potent protective effect against ethanol-induced gastric lesions in rats.
Chemical Information
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CAS No. 158800-83-0
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Molecular Weight 1101.23
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Formula C54H84O23
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SMILES
OC[C@]12[C@](CC(C)(C)[C@@H](OC(/C(C)=C\C)=O)[C@@H]2OC(C)=O)([H])C3=CC[C@@]([C@@]4([C@@]([C@@](CO)([C@@H](O[C@H]5[C@H](O[C@H]6[C@H](O)[C@@H](O)[C@H](O)CO6)[C@@H](O)[C@H](O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O)[C@@H](C(O)=O)O5)CC4)C)([H])CC8)C)([H])[C@]8(C)[C@]3(C)C[C@H]1O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Matsuda H, et al. Effects of escins Ia, Ib, IIa, and IIb from horse chestnut, the seeds of Aesculus hippocastanum L., on acute inflammation in animals. Biol Pharm Bull. 1997;20(10):1092-1095. [Content Brief]
[2]. Matsuda H, et al. Gastroprotections of escins Ia, Ib, IIa, and IIb on ethanol-induced gastric mucosal lesions in rats. Eur J Pharmacol. 1999;373(1):63-70. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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