3 Results for "

37A10

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "37A10" in MCE Product Catalog:

Cat. No.: HY-P99382
CAS No.: 2039148-04-2
Synonyms: JTX 2011; 37A10

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology Cancer

Vopratelimab (JTX-2011) is a humanized immunoglobulin G1-kappa agonist monoclonal antibody that pecifically binds to the Inducible CO-Stimulator of T cells (ICOS). Vopratelimab retains species cross-reactivity with affinities of 0.93 nM to hICOS, 0.46 nM to cynomolgus ICOS, 3.7 nM to rat ICOS, and 0.64 nM to mICOS. Vopratelimab has antitumor immune response .
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Cat. No.: HY-156183
CAS No.: 2989275-31-0
Purity:  98.29%
Target:  

MDM-2/p53 ERK

Research Areas:  

Cancer

Antiproliferative agent-37 (compound 10J) shows anti-proliferative effect by arresting the cells at the G2/M phase of the cell cycle .
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Cat. No.: HY-172890
Target:  

Apoptosis

Research Areas:  

Cancer

Apoptosis inducer 37 (Derivative 10) is an apoptosis inducer. Apoptosis inducer 37 exerts anticancer effects by inducing S-G2/M cell cycle arrest and promoting cell apoptosis. Apoptosis inducer 37 has significant inhibitory activity against HCT116, SKOV3 and HepG2 cancer cells (IC50 values are 24.98 μM, 26.15 μM and 23.09 μM, respectively). Apoptosis inducer 37 has antitumor effects and can be used in ovarian cancer research .
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