4 Results for "

ALK2-IN-1

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "ALK2-IN-1" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-112815
CAS No.: 2254409-25-9
Purity:  99.93%
ALK2-IN-2 is an orally active and selective inhibitor of ALK2 (ACVR1), with an IC50 value of 9 nM, and over 700-fold selectivity against ALK3. ALK2-IN-2 can inhibit oxidative stress and protect endothelial cells .
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Cat. No.: HY-117887
CAS No.: 2141955-96-4
Synonyms: BLU-782; IPN-60130; ALK2-IN-1
Target:  

TGF-β Receptor

Research Areas:  

Cancer

Fidrisertib (BLU-782) is the orally active inhibitor for activin receptor-like kinase 2 (ALK2) that inhibits ALK2 R206H, ALK2, ALK1, ALK6, ALK3, ALK4, TGFβR2 and ALK5 with IC50s of 0.2, 0.6, 3, 24, 45, 65, 67 and 155 nM, respectively .
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Cat. No.: HY-P990022
CAS No.: 2566473-71-8
Synonyms: DS-6016A

Target:  

TGF-β Receptor

Research Areas:  

Metabolic Disease

Prafnosbart (DS-6016A) is an IgG1-kappa, anti-ACVR1 (activin A receptor type 1, ACVRLK2, ALK2, ACVR1A, SKR1) humanized monoclonal antibody. Prafnosbart can be used for bone metabolism disorders research .
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Cat. No.: HY-112414
CAS No.: 216661-57-3
Target:  

TGF-β Receptor

Research Areas:  

Metabolic Disease Cancer

ALK2-IN-7 is a ALK2 (ACVR1) inhibitor. ALK2-IN-7 is applicable to studies related to BMP/ALK2 signaling, anemia associated with iron homeostasis imbalance, and multiple osteochondromas .
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