1 Result for "

167357-83-7

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "167357-83-7" in MCE Product Catalog:

Cat. No.: HY-CE02028
CAS No.: 167357-83-7
Synonyms: Glutaconyl-coenzyme A
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

Glutaconyl-CoA (Glutaconyl-coenzyme A) is a key metabolic intermediate in the mitochondrial catabolic pathways of lysine, hydroxylysine and tryptophan. Glutaconyl-CoA competitively inhibits wild-type glutaryl-CoA dehydrogenase (GCDH) with a Ki value of 1.1 µM. Glutaconyl-CoA is generated via the oxidative decarboxylation of glutaryl-CoA catalyzed by GCDH, and is subsequently further metabolized. Glutaconyl-CoA can be used in the research of type I glutaric aciduria .
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