1 Result for "

2000236-36-0

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "2000236-36-0" in MCE Product Catalog:

Cat. No.: HY-160421
CAS No.: 2000236-36-0
Target:  

Apoptosis

Research Areas:  

Inflammation/Immunology Cancer

TREM2-IN-1 (OPA) is a TREM2 inhibitor derived from oxaliplatin and artesunate. TREM2-IN-1 can relieves immunosuppressive tumor microenvironment and enhancing chemical anticancer efficiency. TREM2-IN-1 deters the tumor growth in mice models bearing MC38 colorectal tumor by reducing the number of CD206 + and CX3CR1 + immunosuppressive macrophages. TREM2-IN-1 also promotes the expansion and infiltration of immunostimulatory dendritic, cytotoxic T and natural killer cells .
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