1 Result for "

21H3RK

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "21H3RK" in MCE Product Catalog:

Cat. No.: HY-P991423
Synonyms: 21H3RK

Target:  

Notch

Research Areas:  

Cancer

MEDI0639 (21H3RK) is a human monoclonal antibody (mAb) targeting DLL4. MEDI0639 inhibits Notch1 binding to Dll4. MEDI0639 reverses Notch1-mediated growth inhibition of human umbilical vein endothelial cells in vitro. MEDI0639 promotes human angiogenesis and reduces the number of vessels covered by smooth muscle actin-positive mural cells. MEDI0639 can be used in Small cell lung cancer and solid tumors research .
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