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1 Result for "
5,7-DCKA (Standard)
" in MedChemExpress (MCE) Product Catalog:
Products (1)
1 Results for "5,7-DCKA (Standard)" in MCE Product Catalog:
Cat. No.: HY-100834R
CAS No.: 131123-76-7
Synonyms: 5,7-DCKA (Standard)
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5,7-Dichlorokynurenic acid (Standard) is the analytical standard of 5,7-Dichlorokynurenic acid (HY-100834). This product is intended for research and analytical applications. 5,7-Dichlorokynurenic acid (5,7-DCKA) is a selective and competitive antagonist of the glycine site on NMDA receptor with a KB of 65 nM. 5,7-Dichlorokynurenic acid reduces NMDA-induced neuron injury. 5,7-Dichlorokynurenic acid increases social interaction time, increases open arm exploration time, disinhibits suppressed conflict responding in rodent models. 5,7-Dichlorokynurenic acid exhibits anxiolytic-like activity in rodent models and supports exploration of glycine’s role in NMDA receptor-mediated synaptic transmission .
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