2 Results for "

79262-46-7

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "79262-46-7" in MCE Product Catalog:

Cat. No.: HY-W747310
CAS No.: 79262-46-7
Synonyms: Cipazoxapine; CGP 19486A
Research Areas:  

Neurological Disease

Savoxepine (Cipazoxapine; CGP 19486A) is a dopamine antagonist with antipsychotic activity. Savoxepine preferentially blocks hippocampal dopamine D2 receptors and also inhibits dopamine-stimulated adenylate cyclase activity. Savoxepine shows strong interactions with α-adrenergic receptors, serotonin 5-HT2 receptors and histamine H1 receptors, and moderate interactions with α2-adrenergic receptors, histamine H2 receptors, serotonin 5-HT1 receptors and cholinergic muscarinic receptors. Savoxepine inhibits dopamine agonist-induced stereotyped behaviors in animals, induces catalepsy in animals, and antagonizes Apomorphine (HY-12723)-induced climbing behavior in mice. Savoxepine can be used in schizophrenia-related research .
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Cat. No.: HY-119385
CAS No.: 79262-47-8
Target:  

Dopamine Receptor

Research Areas:  

Neurological Disease

Savoxepin mesylate is a D2 dopamine receptor (D2 Dopamine Receptor) antagonist with antipsychotic activity. Savoxepin mesylate selectively blocks dopamine D2 receptors in the hippocampus while having no significant effect on D2 receptors in the striatum. This selective blockade helps reduce the risk of extrapyramidal side effects (EPS) .
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